Differential recognition of HIV-stimulated IL-1β and IL-18 secretion through NLR and NAIP signalling in monocyte-derived macrophages

Macrophages are important drivers of pathogenesis and progression to AIDS in HIV infection. The virus in the later phases of the infection is often predominantly macrophage-tropic and this tropism contributes to a chronic inflammatory and immune activation state that is observed in HIV patients. Pat...

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Detalles Bibliográficos
Autores principales: Triantafilou, Kathy, Ward, Christopher J. K., Czubala, Magdalena, Ferris, Robert G., Koppe, Emma, Haffner, Curt, Piguet, Vincent, Patel, Vipulkumar K., Amrine-Madsen, Heather, Modis, Louise K., Masters, Seth L., Triantafilou, Martha
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109768/
https://www.ncbi.nlm.nih.gov/pubmed/33861800
http://dx.doi.org/10.1371/journal.ppat.1009417

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