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ANGPTL8 protein-truncating variant associated with lower serum triglycerides and risk of coronary disease

Protein-truncating variants (PTVs) affecting dyslipidemia risk may point to therapeutic targets for cardiometabolic disease. Our objective was to identify PTVs that were associated with both lipid levels and the risk of coronary artery disease (CAD) or type 2 diabetes (T2D) and assess their possible...

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Detalles Bibliográficos
Autores principales:	Helkkula, Pyry, Kiiskinen, Tuomo, Havulinna, Aki S., Karjalainen, Juha, Koskinen, Seppo, Salomaa, Veikko, Daly, Mark J., Palotie, Aarno, Surakka, Ida, Ripatti, Samuli
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8109807/ https://www.ncbi.nlm.nih.gov/pubmed/33909604 http://dx.doi.org/10.1371/journal.pgen.1009501

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