Improved Overall Survival of Colorectal Cancer under Multidisciplinary Team: A Meta-Analysis

PURPOSE: The purpose of the current meta-analysis was to evaluate whether multidisciplinary team improved overall survival of colorectal cancer. METHODS: PubMed, EMBASE, and Cochrane Library database were searched from inception to October 25, 2020. The hazard ratio (HR) and 95% confidence (CI) of o...

Descripción completa

Detalles Bibliográficos
Autores principales: Peng, Dong, Cheng, Yu-Xi, Cheng, Yong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110396/
https://www.ncbi.nlm.nih.gov/pubmed/33997003
http://dx.doi.org/10.1155/2021/5541613
Descripción
Sumario:PURPOSE: The purpose of the current meta-analysis was to evaluate whether multidisciplinary team improved overall survival of colorectal cancer. METHODS: PubMed, EMBASE, and Cochrane Library database were searched from inception to October 25, 2020. The hazard ratio (HR) and 95% confidence (CI) of overall survival (OS) were calculated. RESULTS: A total of 11 studies with 30814 patients were included in this meta-analysis. After pooling the HRs, the MDT group was associated with better OS compared with the non-MDT group (HR = 0.81, 95% CI 0.69-0.94, p = 0.005). In subgroup analysis of stage IV colorectal cancer, the MDT group was associated with better OS as well (HR = 0.73, 95% CI 0.59-0.90, p = 0.004). However, in terms of postoperative mortality, no significant difference was found between MDT and non-MDT groups (OR = 0.84, 95% CI 0.44-1.61, p = 0.60). CONCLUSION: MDT could improve OS of colorectal cancer patients.

Ejemplares similares