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Clinical pharmacology strategies in supporting drug development and approval of antibody–drug conjugates in oncology
Antibody–drug conjugates (ADCs) are important molecular entities in the treatment of cancer. These conjugates combine the target specificity of monoclonal antibodies with the potent anti-cancer activity of small-molecule therapeutics. The complex structure of ADCs poses unique challenges to characte...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
| Publicado: |
Springer Berlin Heidelberg
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110483/ https://www.ncbi.nlm.nih.gov/pubmed/33792763 http://dx.doi.org/10.1007/s00280-021-04250-0 |