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The combination of dantrolene and nimodipine effectively reduces 5-HT-induced vasospasms in diabetic rats
Diabetics have a higher risk of developing cerebral vasospasms (CVSP) after subarachnoid hemorrhagic stroke than non-diabetics. Serotonin (5-HT) is one of the key vasoconstrictors released in the hemorrhagic blood and an important contributor to the etiology of CVSP. The combination of the ryanodine...
Autores principales: | Román, Marie, García, Laura, Morales, Myrna, Crespo, María J. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110522/ https://www.ncbi.nlm.nih.gov/pubmed/33972638 http://dx.doi.org/10.1038/s41598-021-89338-6 |
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