Quantification of biomarker functionality predicts patient outcomes

Implementation of a quantitative molecular imaging method (iFRET), which determines receptor–ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to...

Descripción completa

Detalles Bibliográficos
Autores principales: Larijani, Banafshé, Miles, James, Ward, Stephen G., Parker, Peter J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110543/
https://www.ncbi.nlm.nih.gov/pubmed/33723395
http://dx.doi.org/10.1038/s41416-021-01291-3
Descripción
Sumario:Implementation of a quantitative molecular imaging method (iFRET), which determines receptor–ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.

Ejemplares similares