Treatment with a DC-SIGN ligand reduces macrophage polarization and diastolic dysfunction in the aging female but not male mouse hearts

Cardiac diastolic dysfunction in aging arises from increased ventricular stiffness caused by inflammation and interstitial fibrosis. The diastolic dysfunction contributes to heart failure with preserved ejection fraction (HFpEF), which in the aging population is more common in women. This report exa...

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Detalles Bibliográficos
Autores principales: Trial, JoAnn, Diaz Lankenau, Rodrigo, Angelini, Aude, Tovar Perez, Jorge E., Taffet, George E., Entman, Mark L., Cieslik, Katarzyna A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2020
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110645/
https://www.ncbi.nlm.nih.gov/pubmed/32851570
http://dx.doi.org/10.1007/s11357-020-00255-4

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110645/
https://www.ncbi.nlm.nih.gov/pubmed/32851570
http://dx.doi.org/10.1007/s11357-020-00255-4

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