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Treatment with a DC-SIGN ligand reduces macrophage polarization and diastolic dysfunction in the aging female but not male mouse hearts
Cardiac diastolic dysfunction in aging arises from increased ventricular stiffness caused by inflammation and interstitial fibrosis. The diastolic dysfunction contributes to heart failure with preserved ejection fraction (HFpEF), which in the aging population is more common in women. This report exa...
Autores principales: | Trial, JoAnn, Diaz Lankenau, Rodrigo, Angelini, Aude, Tovar Perez, Jorge E., Taffet, George E., Entman, Mark L., Cieslik, Katarzyna A. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Springer International Publishing
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110645/ https://www.ncbi.nlm.nih.gov/pubmed/32851570 http://dx.doi.org/10.1007/s11357-020-00255-4 |
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