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Allopurinol ameliorates high fructose diet induced hepatic steatosis in diabetic rats through modulation of lipid metabolism, inflammation, and ER stress pathway

Excess fructose consumption contributes to development obesity, metabolic syndrome, and nonalcoholic fatty liver disease (NAFLD). Uric acid (UA), a metabolite of fructose metabolism, may have a direct role in development of NAFLD, with unclear mechanism. This study aimed to evaluate role of fructose...

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Detalles Bibliográficos
Autores principales: Cho, In-Jin, Oh, Da-Hee, Yoo, Jin, Hwang, You-Cheol, Ahn, Kyu Jeung, Chung, Ho-Yeon, Jeong, Soung Won, Moon, Ju-Young, Lee, Sang-Ho, Lim, Sung-Jig, Jeong, In-Kyung
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110790/
https://www.ncbi.nlm.nih.gov/pubmed/33972568
http://dx.doi.org/10.1038/s41598-021-88872-7