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An infection-induced RhoB-Beclin 1-Hsp90 complex enhances clearance of uropathogenic Escherichia coli

Host cells use several anti-bacterial pathways to defend against pathogens. Here, using a uropathogenic Escherichia coli (UPEC) infection model, we demonstrate that bacterial infection upregulates RhoB, which subsequently promotes intracellular bacteria clearance by inducing LC3 lipidation and autop...

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Detalles Bibliográficos
Autores principales:	Miao, Chunhui, Yu, Mingyu, Pei, Geng, Ma, Zhenyi, Zhang, Lisong, Yang, Jianming, Lv, Junqiang, Zhang, Zhi-Song, Keller, Evan T., Yao, Zhi, Wang, Quan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110956/ https://www.ncbi.nlm.nih.gov/pubmed/33972537 http://dx.doi.org/10.1038/s41467-021-22726-8

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