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Distinct immune signatures in chronic lymphocytic leukemia and Richter syndrome

Richter syndrome (RS) refers to transformation of chronic lymphocytic leukemia (CLL) to an aggressive lymphoma, most commonly diffuse large B-cell lymphoma. RS is known to be associated with a number of genetic alterations such as TP53 and NOTCH1 mutations. However, it is unclear what immune microen...

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Detalles Bibliográficos
Autores principales: Wang, Yucai, Sinha, Sutapa, Wellik, Linda E., Secreto, Charla R., Rech, Karen L., Call, Timothy G., Parikh, Sameer A., Kenderian, Saad S., Muchtar, Eli, Hayman, Suzanne R., Koehler, Amber B., Van Dyke, Daniel L., Leis, Jose F., Slager, Susan L., Dong, Haidong, Kay, Neil E., He, Rong, Ding, Wei
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8110984/
https://www.ncbi.nlm.nih.gov/pubmed/33972504
http://dx.doi.org/10.1038/s41408-021-00477-5