Endoplasmic reticulum stress regulates the intestinal stem cell state through CtBP2

Enforcing differentiation of cancer stem cells is considered as a potential strategy to sensitize colorectal cancer cells to irradiation and chemotherapy. Activation of the unfolded protein response, due to endoplasmic reticulum (ER) stress, causes rapid stem cell differentiation in normal intestina...

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Detalles Bibliográficos
Autores principales: Meijer, Bartolomeus J., Smit, Wouter L., Koelink, Pim J., Westendorp, Barbara F., de Boer, Ruben J., van der Meer, Jonathan H. M., Vermeulen, Jacqueline L. M., Paton, James C., Paton, Adrienne W., Qin, Jun, Dekker, Evelien, Muncan, Vanesa, van den Brink, Gijs R., Heijmans, Jarom
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111031/
https://www.ncbi.nlm.nih.gov/pubmed/33972635
http://dx.doi.org/10.1038/s41598-021-89326-w

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