Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients

Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for severe respiratory and/or circulatory failure. Few data exist on the potential benefit of ECMO in immunocompromised pediatric patients with cancer and/or hematopoietic cell transplantation (HCT). Over a period of 12 years, eleven (1....

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Autores principales: Potratz, Jenny C., Guddorf, Sarah, Ahlmann, Martina, Tekaat, Maria, Rossig, Claudia, Omran, Heymut, Masjosthusmann, Katja, Groll, Andreas H.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111086/
https://www.ncbi.nlm.nih.gov/pubmed/33987100
http://dx.doi.org/10.3389/fonc.2021.664928
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author Potratz, Jenny C.
Guddorf, Sarah
Ahlmann, Martina
Tekaat, Maria
Rossig, Claudia
Omran, Heymut
Masjosthusmann, Katja
Groll, Andreas H.
author_facet Potratz, Jenny C.
Guddorf, Sarah
Ahlmann, Martina
Tekaat, Maria
Rossig, Claudia
Omran, Heymut
Masjosthusmann, Katja
Groll, Andreas H.
author_sort Potratz, Jenny C.
collection PubMed
description Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for severe respiratory and/or circulatory failure. Few data exist on the potential benefit of ECMO in immunocompromised pediatric patients with cancer and/or hematopoietic cell transplantation (HCT). Over a period of 12 years, eleven (1.9%) of 572 patients with new diagnosis of leukemia/lymphoma and nine (3.5%) of 257 patients post allogeneic HCT underwent ECMO at our center. Five (45%) and two (22%) patients, respectively, survived to hospital discharge with a median event-free survival of 4.2 years. Experiences and outcomes in this cohort may aid clinicians and families when considering ECMO for individual patients.
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spelling pubmed-81110862021-05-12 Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients Potratz, Jenny C. Guddorf, Sarah Ahlmann, Martina Tekaat, Maria Rossig, Claudia Omran, Heymut Masjosthusmann, Katja Groll, Andreas H. Front Oncol Oncology Extracorporeal membrane oxygenation (ECMO) is a rescue therapy for severe respiratory and/or circulatory failure. Few data exist on the potential benefit of ECMO in immunocompromised pediatric patients with cancer and/or hematopoietic cell transplantation (HCT). Over a period of 12 years, eleven (1.9%) of 572 patients with new diagnosis of leukemia/lymphoma and nine (3.5%) of 257 patients post allogeneic HCT underwent ECMO at our center. Five (45%) and two (22%) patients, respectively, survived to hospital discharge with a median event-free survival of 4.2 years. Experiences and outcomes in this cohort may aid clinicians and families when considering ECMO for individual patients. Frontiers Media S.A. 2021-04-27 /pmc/articles/PMC8111086/ /pubmed/33987100 http://dx.doi.org/10.3389/fonc.2021.664928 Text en Copyright © 2021 Potratz, Guddorf, Ahlmann, Tekaat, Rossig, Omran, Masjosthusmann and Groll https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Oncology
Potratz, Jenny C.
Guddorf, Sarah
Ahlmann, Martina
Tekaat, Maria
Rossig, Claudia
Omran, Heymut
Masjosthusmann, Katja
Groll, Andreas H.
Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients
title Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients
title_full Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients
title_fullStr Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients
title_full_unstemmed Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients
title_short Extracorporeal Membrane Oxygenation in Children With Cancer or Hematopoietic Cell Transplantation: Single-Center Experience in 20 Consecutive Patients
title_sort extracorporeal membrane oxygenation in children with cancer or hematopoietic cell transplantation: single-center experience in 20 consecutive patients
topic Oncology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111086/
https://www.ncbi.nlm.nih.gov/pubmed/33987100
http://dx.doi.org/10.3389/fonc.2021.664928
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