Cargando…
Activation of GSK3 Prevents Termination of TNF-Induced Signaling
BACKGROUND: Termination of TNF-induced signaling plays a key role in the resolution of inflammation with dysregulations leading to severe pathophysiological conditions (sepsis, chronic inflammatory disease, cancer). Since a recent phospho-proteome analysis in human monocytes suggested GSK3 as a rele...
Autores principales: | Welz, Bastian, Bikker, Rolf, Hoffmeister, Leonie, Diekmann, Mareike, Christmann, Martin, Brand, Korbinian, Huber, René |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Dove
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111165/ https://www.ncbi.nlm.nih.gov/pubmed/33986607 http://dx.doi.org/10.2147/JIR.S300806 |
Ejemplares similares
-
TNF Tolerance in Monocytes and Macrophages: Characteristics and Molecular Mechanisms
por: Huber, René, et al.
Publicado: (2017) -
Proteome and Phosphoproteome Analysis in TNF Long Term-Exposed Primary Human Monocytes
por: Welz, Bastian, et al.
Publicado: (2019) -
GSK3: A Kinase Balancing Promotion and Resolution of Inflammation
por: Hoffmeister, Leonie, et al.
Publicado: (2020) -
MARCKS Is an Essential Regulator of Reactive Oxygen Species Production in the Monocytic Cell Type
por: Huber, René, et al.
Publicado: (2022) -
C/EBPβ-LAP*/LAP Expression Is Mediated by RSK/eIF4B-Dependent Signalling and Boosted by Increased Protein Stability in Models of Monocytic Differentiation
por: Huber, René, et al.
Publicado: (2015)