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Hidden in Plain View: Discovery of Chimeric Diabetogenic CD4 T Cell Neo-Epitopes
The T cell antigens driving autoimmune Type 1 Diabetes (T1D) have been pursued for more than three decades. When diabetogenic CD4 T cell clones and their relevant MHCII antigen presenting alleles were first identified in rodents and humans, the path to discovering the peptide epitopes within pancrea...
| Autores principales: | , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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Frontiers Media S.A.
2021
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111216/ https://www.ncbi.nlm.nih.gov/pubmed/33986758 http://dx.doi.org/10.3389/fimmu.2021.669986 |