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Investigating the Role of Guanosine on Human Neuroblastoma Cell Differentiation and the Underlying Molecular Mechanisms

Neuroblastoma arises from neural crest cell precursors failing to complete the process of differentiation. Thus, agents helping tumor cells to differentiate into normal cells can represent a valid therapeutic strategy. Here, we evaluated whether guanosine (GUO), a natural purine nucleoside, which is...

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Detalles Bibliográficos
Autores principales: Belluardo, Natale, Mudò, Giuseppa, Di Liberto, Valentina, Frinchi, Monica, Condorelli, Daniele F., Traversa, Ugo, Ciruela, Francisco, Ciccarelli, Renata, Di Iorio, Patrizia, Giuliani, Patricia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111303/
https://www.ncbi.nlm.nih.gov/pubmed/33986683
http://dx.doi.org/10.3389/fphar.2021.658806