DNA damage response- and JAK-dependent regulation of PD-L1 expression in head and neck squamous cell carcinoma (HNSCC) cells exposed to 5-fluorouracil (5-FU)

OBJECTIVES: The immune checkpoint molecule PD-L1 (CD274) is a crucial regulator of the tumor immune response. Its expression has been reported in the therapeutic context in Head and Neck Squamous Cell Carcinoma (HNSCC), but it remains unclear how therapeutically approved molecules regulate PD-L1 exp...

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Detalles Bibliográficos
Autores principales: Lailler, Claire, Lamuraglia, Michele, Racine, Floriane, Louandre, Christophe, Godin, Corinne, Chauffert, Bruno, Galmiche, Antoine, Saidak, Zuzana
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111315/
https://www.ncbi.nlm.nih.gov/pubmed/33951601
http://dx.doi.org/10.1016/j.tranon.2021.101110

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111315/
https://www.ncbi.nlm.nih.gov/pubmed/33951601
http://dx.doi.org/10.1016/j.tranon.2021.101110

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