3D heterospecies spheroids of pancreatic stroma and cancer cells demonstrate key phenotypes of pancreatic ductal adenocarcinoma

Pancreatic ductal adenocarcinoma (PDAC) is one of the most lethal malignancies, partly due to the dense desmoplasia and a lack of suitable model systems to study. In the present work, we developed a 3D heterospecies spheroid model to study the microenvironmental interactions between tumor cells and...

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Detalles Bibliográficos
Autores principales: Liu, Xinyuan, Gündel, Beate, Li, Xidan, Liu, Jianping, Wright, Anthony, Löhr, Matthias, Arvidsson, Gustav, Heuchel, Rainer
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Neoplasia Press 2021
Materias:
Original Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111319/
https://www.ncbi.nlm.nih.gov/pubmed/33946033
http://dx.doi.org/10.1016/j.tranon.2021.101107

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