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Quantitative high-throughput assay to measure MC4R-induced intracellular calcium

The melanocortin-4 receptor (MC4R), a critical G-protein-coupled receptor (GPCR) regulating energy homeostasis, activates multiple signalling pathways, including mobilisation of intracellular calcium ([Ca(2+)](i)). However, very little is known about the physiological significance of MC4R-induced [C...

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Detalles Bibliográficos
Autores principales:	Kumar, Shree Senthil, Ward, Marie-Louise, Mountjoy, Kathleen Grace
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Bioscientifica Ltd 2021
Materias:	Research
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111326/ https://www.ncbi.nlm.nih.gov/pubmed/33739935 http://dx.doi.org/10.1530/JME-20-0285

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