Cargando…

Radiation Increases Bioavailability of Lisinopril, a Mitigator of Radiation-Induced Toxicities

There are no FDA-approved drugs to mitigate the delayed effects of radiation exposure that may occur after a radiological attack or nuclear accident. To date, angiotensin-converting enzyme inhibitors are one of the most successful candidates for mitigation of hematopoietic, lung, kidney, and brain i...

Descripción completa

Detalles Bibliográficos
Autores principales:	Medhora, Meetha, Phadnis, Preeya, Narayanan, Jayashree, Gasperetti, Tracy, Zielonka, Jacek, Moulder, John E., Fish, Brian L., Szabo, Aniko
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Frontiers Media S.A. 2021
Materias:	Pharmacology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111401/ https://www.ncbi.nlm.nih.gov/pubmed/33986677 http://dx.doi.org/10.3389/fphar.2021.646076

Ejemplares similares

Wound Trauma Exacerbates Acute, but not Delayed, Effects of Radiation in Rats: Mitigation by Lisinopril
por: Medhora, Meetha, et al.
Publicado: (2020)

Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes
por: Gasperetti, Tracy, et al.
Publicado: (2021)

Lisinopril Mitigates Radiation-Induced Mitochondrial Defects in Rat Heart and Blood Cells
por: Ortiz de Choudens, Saryleine, et al.
Publicado: (2022)

Corrigendum: Polypharmacy to Mitigate Acute and Delayed Radiation Syndromes
por: Gasperetti, Tracy, et al.
Publicado: (2021)

Dose-modifying factor for captopril for mitigation of radiation injury to normal lung
por: Medhora, Meetha, et al.
Publicado: (2012)

Biomarkers to Predict Lethal Radiation Injury to the Rat Lung
por: Medhora, Meetha, et al.
Publicado: (2023)

Angiotensin Converting Enzyme Inhibitors Mitigate Collagen Synthesis Induced by a Single Dose of Radiation to the Whole Thorax
por: Kma, Lakhan, et al.
Publicado: (2012)

Three-dimensional vascular and metabolic imaging using inverted autofluorescence
por: Mehrvar, Shima, et al.
Publicado: (2021)

Changes in miRNA in the lung and whole blood after whole thorax irradiation in rats
por: Gao, Feng, et al.
Publicado: (2017)

Classes of Drugs that Mitigate Radiation Syndromes
por: Micewicz, Ewa D., et al.
Publicado: (2021)

Brain-derived neurotrophic factor promotes immune reconstitution following radiation injury via activation of bone marrow mesenchymal stem cells
por: Sharma, Guru Prasad, et al.
Publicado: (2021)

Whole-thorax irradiation induces hypoxic respiratory failure, pleural effusions and cardiac remodeling
por: Medhora, Meetha, et al.
Publicado: (2015)

Baicalein Mitigates Radiation-Induced Enteritis by Improving Endothelial Dysfunction
por: Jang, Hyosun, et al.
Publicado: (2019)

Pharmacology, Toxicity, Bioavailability, and Formulation of Magnolol: An Update
por: Lin, Yiping, et al.
Publicado: (2021)

Potential Role of Lisinopril in Reducing Atherosclerotic Risk: Evidence of an Antioxidant Effect in Human Cardiomyocytes Cell Line
por: Scisciola, Lucia, et al.
Publicado: (2022)

Pyrrolidine Dithiocarbamate Might Mitigate Radiation-Induced Heart Damage at an Early Stage in Rats
por: Wu, Yajing, et al.
Publicado: (2022)

Mitigation of Ionizing Radiation-Induced Gastrointestinal Damage by Insulin-Like Growth Factor-1 in Mice
por: Pejchal, Jaroslav, et al.
Publicado: (2022)

Oral Lisinopril Raises Tissue Levels of ACE2, the SARS-CoV-2 Receptor, in Healthy Male and Female Mice
por: Brooks, Steven D., et al.
Publicado: (2022)

Strategies for prediction and mitigation of radiation-induced liver toxicity
por: Toesca, Diego A S, et al.
Publicado: (2018)

Memantine for Mitigation of Neurocognitive Toxicity Following Radiation to the Brain
por: Cunningham, Danielle A., et al.
Publicado: (2021)

Strategies to Mitigate Chemotherapy and Radiation Toxicities That Affect Eating
por: Anderson, Peter M., et al.
Publicado: (2021)

An optimized method for the isolation of urinary extracellular vesicles for molecular phenotyping: detection of biomarkers for radiation exposure
por: Hinzman, Charles P., et al.
Publicado: (2022)

Comparative Effect of Lisinopril and Fosinopril in Mitigating Learning and Memory Deficit in Scopolamine-Induced Amnesic Rats
por: Deb, Debasree, et al.
Publicado: (2015)

Metformin mitigates radiation toxicity exerting antioxidant and genoprotective properties
por: Karmanova, Ekaterina E., et al.
Publicado: (2023)

Blocking TRAIL-DR5 signaling pathway with soluble death receptor 5 fusion protein mitigates radiation-induced injury
por: Zhao, Danyang, et al.
Publicado: (2023)

Synthesis and Characterization of Compounds Related to Lisinopril
por: Raghava Reddy, Ambati V., et al.
Publicado: (2016)

Treatment of Hypertension with Combination of Lisinopril/Hydrochlorothiazide
por: Sukalo, Aziz, et al.
Publicado: (2016)

Lisinopril-Induced Acute Necrotizing Pancreatitis
por: Syed, Salman B, et al.
Publicado: (2021)

Lisinopril: Severe angioedema: case report
Publicado: (2021)

Sulforaphane Potentiates Anticancer Effects of Doxorubicin and Cisplatin and Mitigates Their Toxic Effects
por: Calcabrini, Cinzia, et al.
Publicado: (2020)

Biological sex differences in renin angiotensin system enzymes ACE and ACE2 regulate normal tissue response to radiation injury
por: Sharma, Guru Prasad, et al.
Publicado: (2023)

Pharmacological targeting of the thrombomodulin–protein C pathway mitigates radiation toxicity
por: Geiger, Hartmut, et al.
Publicado: (2012)

A synthetic superoxide dismutase/catalase mimetic EUK-207 mitigates radiation dermatitis and promotes wound healing in irradiated rat skin
por: Doctrow, Susan R., et al.
Publicado: (2012)

The Angiotensin-Converting Enzyme Inhibitor Lisinopril Mitigates Memory and Motor Deficits in a Drosophila Model of Alzheimer’s Disease
por: Thomas, Jimiece, et al.
Publicado: (2021)

An Unexpected Case of Lisinopril-Associated Severe Hyponatremia
por: Jiang, Yiran, et al.
Publicado: (2020)

Hydrochlorothiazide/lisinopril/metoprolol: Hypovolaemia: case report
Publicado: (2021)

Another Case of Lisinopril-Induced Acute Pancreatitis
por: Baum, Jeffrey, et al.
Publicado: (2021)

Mitigation of acetaminophen-induced liver toxicity by the novel phosphatidylinositol 3-kinase inhibitor alpelisib
por: Shaker, Mohamed E., et al.
Publicado: (2023)

Extracellular Vesicles for the Treatment of Radiation Injuries
por: Nanduri, Lalitha Sarad Yamini, et al.
Publicado: (2021)

Mycolactone as Analgesic: Subcutaneous Bioavailability Parameters
por: Babonneau, Jérémie, et al.
Publicado: (2019)

Cannot write session to /tmp/vufind_sessions/sess_pvo691ot5ad8tu1dpfv284g7in