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Optic pathway gliosarcoma: A very rare location for a rare disease

Gliosarcoma, a variant of glioblastoma, is a rare and aggressive tumor of the central nervous system (CNS) composed of glial and sarcomatous tissues. Up to now, there are only 2 reported cases of gliosarcoma of the optical pathway. We report a case from March 2018 of a 53-year-old male patient prese...

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Autores principales: Prado, Renato Masson de Almeida, Tamura, Bruno Pierri, Gomez, Gustavo Dalul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111437/
https://www.ncbi.nlm.nih.gov/pubmed/34007379
http://dx.doi.org/10.1016/j.radcr.2021.04.001
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author Prado, Renato Masson de Almeida
Tamura, Bruno Pierri
Gomez, Gustavo Dalul
author_facet Prado, Renato Masson de Almeida
Tamura, Bruno Pierri
Gomez, Gustavo Dalul
author_sort Prado, Renato Masson de Almeida
collection PubMed
description Gliosarcoma, a variant of glioblastoma, is a rare and aggressive tumor of the central nervous system (CNS) composed of glial and sarcomatous tissues. Up to now, there are only 2 reported cases of gliosarcoma of the optical pathway. We report a case from March 2018 of a 53-year-old male patient presented with 6 months’ of right fronto-orbital pulsatile headache, behavior changes, and visual loss. The MRI study showed an expansile optic pathway lesion involving the chiasm and right optic nerve. The diagnosis of gliosarcoma was obtained by open brain biopsy and immunohistochemical analysis. Although gliosarcoma is rare, it should be considered a differential diagnosis even in optic pathway tumors in older patients. The experience of the neuropathologist with a trained eye can be the differential in the accurate diagnostic process. Optic pathway, Gliosarcoma, Glioblastoma, Magnetic resonance imaging
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spelling pubmed-81114372021-05-17 Optic pathway gliosarcoma: A very rare location for a rare disease Prado, Renato Masson de Almeida Tamura, Bruno Pierri Gomez, Gustavo Dalul Radiol Case Rep Case Report Gliosarcoma, a variant of glioblastoma, is a rare and aggressive tumor of the central nervous system (CNS) composed of glial and sarcomatous tissues. Up to now, there are only 2 reported cases of gliosarcoma of the optical pathway. We report a case from March 2018 of a 53-year-old male patient presented with 6 months’ of right fronto-orbital pulsatile headache, behavior changes, and visual loss. The MRI study showed an expansile optic pathway lesion involving the chiasm and right optic nerve. The diagnosis of gliosarcoma was obtained by open brain biopsy and immunohistochemical analysis. Although gliosarcoma is rare, it should be considered a differential diagnosis even in optic pathway tumors in older patients. The experience of the neuropathologist with a trained eye can be the differential in the accurate diagnostic process. Optic pathway, Gliosarcoma, Glioblastoma, Magnetic resonance imaging Elsevier 2021-04-30 /pmc/articles/PMC8111437/ /pubmed/34007379 http://dx.doi.org/10.1016/j.radcr.2021.04.001 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open access article under the CC BY-NC-ND license (http://creativecommons.org/licenses/by-nc-nd/4.0/).
spellingShingle Case Report
Prado, Renato Masson de Almeida
Tamura, Bruno Pierri
Gomez, Gustavo Dalul
Optic pathway gliosarcoma: A very rare location for a rare disease
title Optic pathway gliosarcoma: A very rare location for a rare disease
title_full Optic pathway gliosarcoma: A very rare location for a rare disease
title_fullStr Optic pathway gliosarcoma: A very rare location for a rare disease
title_full_unstemmed Optic pathway gliosarcoma: A very rare location for a rare disease
title_short Optic pathway gliosarcoma: A very rare location for a rare disease
title_sort optic pathway gliosarcoma: a very rare location for a rare disease
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111437/
https://www.ncbi.nlm.nih.gov/pubmed/34007379
http://dx.doi.org/10.1016/j.radcr.2021.04.001
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