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Uncovering a novel role of PLCβ4 in selectively mediating TCR signaling in CD8(+) but not CD4(+) T cells

Because of their common signaling molecules, the main T cell receptor (TCR) signaling cascades in CD4(+) and CD8(+) T cells are considered qualitatively identical. Herein, we show that TCR signaling in CD8(+) T cells is qualitatively different from that in CD4(+) T cells, since CD8α ignites another...

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Detalles Bibliográficos
Autores principales:	Sasai, Miwa, Ma, Ji Su, Okamoto, Masaaki, Nishino, Kohei, Nagaoka, Hikaru, Takashima, Eizo, Pradipta, Ariel, Lee, Youngae, Kosako, Hidetaka, Suh, Pann-Ghill, Yamamoto, Masahiro
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Rockefeller University Press 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111461/ https://www.ncbi.nlm.nih.gov/pubmed/33970189 http://dx.doi.org/10.1084/jem.20201763

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