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Testicular cancer metastasis to the soft tissue: A case report and review of the literature

While germ cell testicular cancer is rare and only accounts for 1% of cancers in males, it is the most common solid malignancy among men between 14 and 44 years of age. Testicular cancer can be surgically excised by orchiectomy and is highly responsive to both chemotherapy and radiation therapy. The...

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Autores principales: Crain, Matthew A., Lakhani, Dhairya A., Balar, Aneri B., Martin, Daniel, Lombard, Cara B, Nguyen, Thuan-Phuong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111471/
https://www.ncbi.nlm.nih.gov/pubmed/34007386
http://dx.doi.org/10.1016/j.radcr.2021.04.004
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author Crain, Matthew A.
Lakhani, Dhairya A.
Balar, Aneri B.
Martin, Daniel
Lombard, Cara B
Nguyen, Thuan-Phuong
author_facet Crain, Matthew A.
Lakhani, Dhairya A.
Balar, Aneri B.
Martin, Daniel
Lombard, Cara B
Nguyen, Thuan-Phuong
author_sort Crain, Matthew A.
collection PubMed
description While germ cell testicular cancer is rare and only accounts for 1% of cancers in males, it is the most common solid malignancy among men between 14 and 44 years of age. Testicular cancer can be surgically excised by orchiectomy and is highly responsive to both chemotherapy and radiation therapy. Therefore, testicular tumors generally have the best cancer prognoses, especially since the majority are localized in the initial stage. However, long-term outcome depends on the potential for germ cell testicular cancer to metastasize, both proximal to the testicles and distally throughout the body. Germ cell testicular cancer metastasis to soft tissue, including the trunk, and extremities, appears to be exceedingly rare, as reflected in the extremely limited number of published cases (total of seven patients reported in literature). Vague symptomatology, delayed medical attention, and inconsistent treatment compliance may contribute to testicular soft tissue metastasis and underreporting of these tumors. Here, we report a case of metastatic non–seminomatous germ cell testicular cancer with a large necrotizing, ulcerative mass in the left Iliopsoas muscle and posterior abdominal wall.
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spelling pubmed-81114712021-05-17 Testicular cancer metastasis to the soft tissue: A case report and review of the literature Crain, Matthew A. Lakhani, Dhairya A. Balar, Aneri B. Martin, Daniel Lombard, Cara B Nguyen, Thuan-Phuong Radiol Case Rep Case Report While germ cell testicular cancer is rare and only accounts for 1% of cancers in males, it is the most common solid malignancy among men between 14 and 44 years of age. Testicular cancer can be surgically excised by orchiectomy and is highly responsive to both chemotherapy and radiation therapy. Therefore, testicular tumors generally have the best cancer prognoses, especially since the majority are localized in the initial stage. However, long-term outcome depends on the potential for germ cell testicular cancer to metastasize, both proximal to the testicles and distally throughout the body. Germ cell testicular cancer metastasis to soft tissue, including the trunk, and extremities, appears to be exceedingly rare, as reflected in the extremely limited number of published cases (total of seven patients reported in literature). Vague symptomatology, delayed medical attention, and inconsistent treatment compliance may contribute to testicular soft tissue metastasis and underreporting of these tumors. Here, we report a case of metastatic non–seminomatous germ cell testicular cancer with a large necrotizing, ulcerative mass in the left Iliopsoas muscle and posterior abdominal wall. Elsevier 2021-04-30 /pmc/articles/PMC8111471/ /pubmed/34007386 http://dx.doi.org/10.1016/j.radcr.2021.04.004 Text en © 2021 The Authors. Published by Elsevier Inc. on behalf of University of Washington. https://creativecommons.org/licenses/by/4.0/This is an open access article under the CC BY license (http://creativecommons.org/licenses/by/4.0/).
spellingShingle Case Report
Crain, Matthew A.
Lakhani, Dhairya A.
Balar, Aneri B.
Martin, Daniel
Lombard, Cara B
Nguyen, Thuan-Phuong
Testicular cancer metastasis to the soft tissue: A case report and review of the literature
title Testicular cancer metastasis to the soft tissue: A case report and review of the literature
title_full Testicular cancer metastasis to the soft tissue: A case report and review of the literature
title_fullStr Testicular cancer metastasis to the soft tissue: A case report and review of the literature
title_full_unstemmed Testicular cancer metastasis to the soft tissue: A case report and review of the literature
title_short Testicular cancer metastasis to the soft tissue: A case report and review of the literature
title_sort testicular cancer metastasis to the soft tissue: a case report and review of the literature
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111471/
https://www.ncbi.nlm.nih.gov/pubmed/34007386
http://dx.doi.org/10.1016/j.radcr.2021.04.004
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