Warburg effect-promoted exosomal circ_0072083 releasing up-regulates NANGO expression through multiple pathways and enhances temozolomide resistance in glioma

BACKGROUND: Temozolomide (TMZ) resistance limits its application in glioma. Exosome can carry circular RNAs (circRNAs) to regulate drug resistance via sponging microRNAs (miRNAs). miRNAs can control mRNA expression by regulate the interaction with 3’UTR and methylation. Nanog homeobox (NANOG) is an...

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Detalles Bibliográficos
Autores principales: Ding, Chenyu, Yi, Xuehan, Chen, Xiangrong, Wu, Zanyi, You, Honghai, Chen, Xiaoyong, Zhang, Gaoqi, Sun, Yong, Bu, Xingyao, Wu, Xiyue, Lin, Zhangya, Gu, Jianjun, Lin, Yuanxiang, Kang, Dezhi
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111743/
https://www.ncbi.nlm.nih.gov/pubmed/33975615
http://dx.doi.org/10.1186/s13046-021-01942-6

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