Cryopreservation of human cancers conserves tumour heterogeneity for single-cell multi-omics analysis

BACKGROUND: High throughput single-cell RNA sequencing (scRNA-Seq) has emerged as a powerful tool for exploring cellular heterogeneity among complex human cancers. scRNA-Seq studies using fresh human surgical tissue are logistically difficult, preclude histopathological triage of samples, and limit...

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Detalles Bibliográficos
Autores principales: Wu, Sunny Z., Roden, Daniel L., Al-Eryani, Ghamdan, Bartonicek, Nenad, Harvey, Kate, Cazet, Aurélie S., Chan, Chia-Ling, Junankar, Simon, Hui, Mun N., Millar, Ewan A., Beretov, Julia, Horvath, Lisa, Joshua, Anthony M., Stricker, Phillip, Wilmott, James S., Quek, Camelia, Long, Georgina V., Scolyer, Richard A., Yeung, Bertrand Z., Segara, Davendra, Mak, Cindy, Warrier, Sanjay, Powell, Joseph E., O’Toole, Sandra, Lim, Elgene, Swarbrick, Alexander
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111910/
https://www.ncbi.nlm.nih.gov/pubmed/33971952
http://dx.doi.org/10.1186/s13073-021-00885-z

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