The potential role of the extracellular matrix in the activity of trabectedin in UPS and L-sarcoma: evidences from a patient‐derived primary culture case series in tridimensional and zebrafish models

BACKGROUND: Soft tissue sarcomas (STS) are a rare group of solid neoplasm including among others liposarcoma, leiomyosarcoma (L-sarcoma) and undifferentiated pleomorphic sarcoma (UPS) entities. The current first-line treatment is represented by anthracycline based- regimens, second-line may include...

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Detalles Bibliográficos
Autores principales: De Vita, Alessandro, Recine, Federica, Miserocchi, Giacomo, Pieri, Federica, Spadazzi, Chiara, Cocchi, Claudia, Vanni, Silvia, Liverani, Chiara, Farnedi, Anna, Fabbri, Francesco, Fausti, Valentina, Casadei, Roberto, Brandolini, Francesca, Ercolani, Giorgio, Cavaliere, Davide, Bongiovanni, Alberto, Riva, Nada, Gurrieri, Lorena, Di Menna, Giandomenico, Calpona, Sebastiano, Debonis, Silvia Angela, Mercatali, Laura, Ibrahim, Toni
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111914/
https://www.ncbi.nlm.nih.gov/pubmed/33975637
http://dx.doi.org/10.1186/s13046-021-01963-1

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111914/
https://www.ncbi.nlm.nih.gov/pubmed/33975637
http://dx.doi.org/10.1186/s13046-021-01963-1

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