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The potential role of the extracellular matrix in the activity of trabectedin in UPS and L-sarcoma: evidences from a patient‐derived primary culture case series in tridimensional and zebrafish models
BACKGROUND: Soft tissue sarcomas (STS) are a rare group of solid neoplasm including among others liposarcoma, leiomyosarcoma (L-sarcoma) and undifferentiated pleomorphic sarcoma (UPS) entities. The current first-line treatment is represented by anthracycline based- regimens, second-line may include...
Autores principales: | De Vita, Alessandro, Recine, Federica, Miserocchi, Giacomo, Pieri, Federica, Spadazzi, Chiara, Cocchi, Claudia, Vanni, Silvia, Liverani, Chiara, Farnedi, Anna, Fabbri, Francesco, Fausti, Valentina, Casadei, Roberto, Brandolini, Francesca, Ercolani, Giorgio, Cavaliere, Davide, Bongiovanni, Alberto, Riva, Nada, Gurrieri, Lorena, Di Menna, Giandomenico, Calpona, Sebastiano, Debonis, Silvia Angela, Mercatali, Laura, Ibrahim, Toni |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111914/ https://www.ncbi.nlm.nih.gov/pubmed/33975637 http://dx.doi.org/10.1186/s13046-021-01963-1 |
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