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Orthotopic model of lung cancer: isolation of bone micro-metastases after tumor escape from Osimertinib treatment

BACKGROUND: Osimertinib is a third generation tyrosine kinase inhibitor (TKI) that targets the epidermal growth factor receptor (EGFR) in lung cancer. However, although this molecule is not subject to some of the resistance mechanisms observed in response to first generation TKIs, ultimately, patien...

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Detalles Bibliográficos
Autores principales:	Jarry, Ulrich, Bostoën, Mégane, Pineau, Raphaël, Chaillot, Laura, Mennessier, Valentine, Montagne, Pierre, Motte, Emilie, Gournay, Marjorie, Le Goff, Arnaud, Guillaudeux, Thierry, Pedeux, Rémy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BioMed Central 2021
Materias:	Technical Advance
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111918/ https://www.ncbi.nlm.nih.gov/pubmed/33971844 http://dx.doi.org/10.1186/s12885-021-08205-9

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