Cargando…
Epigenomic tensor predicts disease subtypes and reveals constrained tumor evolution
Understanding the epigenomic evolution and specificity of disease subtypes from complex patient data remains a major biomedical problem. We here present DeCET (decomposition and classification of epigenomic tensors), an integrative computational approach for simultaneously analyzing hierarchical het...
Autores principales: | Leistico, Jacob R., Saini, Priyanka, Futtner, Christopher R., Hejna, Miroslav, Omura, Yasuhiro, Soni, Pritin N., Sandlesh, Poorva, Milad, Magdy, Wei, Jian-Jun, Bulun, Serdar, Parker, J. Brandon, Barish, Grant D., Song, Jun S., Chakravarti, Debabrata |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111960/ https://www.ncbi.nlm.nih.gov/pubmed/33789109 http://dx.doi.org/10.1016/j.celrep.2021.108927 |
Ejemplares similares
-
A MYC inhibitor selectively alters the MYC and MAX cistromes and modulates the epigenomic landscape to regulate target gene expression
por: Holmes, Austin G., et al.
Publicado: (2022) -
Dysfunctional MnSOD leads to redox dysregulation and activation of prosurvival AKT signaling in uterine leiomyomas
por: Vidimar, Vania, et al.
Publicado: (2016) -
Discriminative and Distinct Phenotyping by Constrained Tensor Factorization
por: Kim, Yejin, et al.
Publicado: (2017) -
Application of ex-vivo spheroid model system for the analysis of senescence and senolytic phenotypes in uterine leiomyoma
por: Xie, Jia, et al.
Publicado: (2018) -
Dynamic enhancers control skeletal muscle identity and reprogramming
por: Ramachandran, Krithika, et al.
Publicado: (2019)