Super-resolution visualization and modeling of human chromosomal regions reveals cohesin-dependent loop structures

BACKGROUND: The 3D organization of the chromatin fiber in cell nuclei plays a key role in the regulation of gene expression. Genome-wide techniques to score DNA-DNA contacts, such as Hi-C, reveal the partitioning of chromosomes into epigenetically defined active and repressed compartments and smalle...

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Detalles Bibliográficos
Autores principales: Hao, Xian, Parmar, Jyotsana J., Lelandais, Benoît, Aristov, Andrey, Ouyang, Wei, Weber, Christian, Zimmer, Christophe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111965/
https://www.ncbi.nlm.nih.gov/pubmed/33975635
http://dx.doi.org/10.1186/s13059-021-02343-w

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8111965/
https://www.ncbi.nlm.nih.gov/pubmed/33975635
http://dx.doi.org/10.1186/s13059-021-02343-w

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