IL-9-triggered lncRNA Gm13568 regulates Notch1 in astrocytes through interaction with CBP/P300: contribute to the pathogenesis of experimental autoimmune encephalomyelitis

BACKGROUND: Interleukin 9 (IL-9), produced mainly by T helper 9 (Th9) cells, has been recognized as an important regulator in multiple sclerosis (MS) and its animal model, experimental autoimmune encephalomyelitis (EAE). Astrocytes respond to IL-9 and reactive astrocytes always associate with blood-...

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Detalles Bibliográficos
Autores principales: Liu, Xiaomei, Zhou, Feng, Wang, Weixiao, Chen, Guofang, Zhang, Qingxiu, Lv, Ruixue, Zhao, Zijun, Li, Xiangyang, Yu, Qian, Meves, Jessica M., Hua, Hui, Li, Xiaocui, Wang, Xiaotian, Sun, Hong, Gao, Dianshuai
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2021
Materias:
Research
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112022/
https://www.ncbi.nlm.nih.gov/pubmed/33971906
http://dx.doi.org/10.1186/s12974-021-02156-5

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