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Designing and Development of a Tandem Bivalent Nanobody against VEGF(165)
BACKGROUND: Inhibition of angiogenesis using monoclonal antibodies is an effective strategy in cancer therapy. However, they could not penetrate sufficiently into solid tumors. Antibody fragments have solved this issue. However, they suffer from short in vivo half-life. In the current study, a tande...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Avicenna Research Institute
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112138/ https://www.ncbi.nlm.nih.gov/pubmed/34012520 http://dx.doi.org/10.18502/ajmb.v13i2.5519 |