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Designing and Development of a Tandem Bivalent Nanobody against VEGF(165)

BACKGROUND: Inhibition of angiogenesis using monoclonal antibodies is an effective strategy in cancer therapy. However, they could not penetrate sufficiently into solid tumors. Antibody fragments have solved this issue. However, they suffer from short in vivo half-life. In the current study, a tande...

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Detalles Bibliográficos
Autores principales:	Khodabakhsh, Farnaz, Salimian, Morteza, Ziaee, Pardis, Kazemi-Lomedasht, Fatemeh, Behdani, Mahdi, Ahangari Cohan, Reza
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Avicenna Research Institute 2021
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112138/ https://www.ncbi.nlm.nih.gov/pubmed/34012520 http://dx.doi.org/10.18502/ajmb.v13i2.5519

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