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Genome Edited Sirt1-Overexpressing Human Mesenchymal Stem Cells Exhibit Therapeutic Effects in Treating Collagen-Induced Arthritis

Even though mesenchymal stem cells (MSCs) are known for cartilage regeneration, their therapeutic efficacy needs to be enhanced. In the present study, we produced genome-edited silent information regulator 2 type 1 (Sirt1)-overexpressing MSCs, and evaluated their therapeutic potential in a damaged c...

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Detalles Bibliográficos
Autores principales:	Chae, Dong-Sik, Han, Seongho, Lee, Min-Kyung, Kim, Sung-Whan
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112166/ https://www.ncbi.nlm.nih.gov/pubmed/33935044 http://dx.doi.org/10.14348/molcells.2021.0037

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