Cargando…

Overexpression of COMP-Angiopoietin-1 in K14-Expressing Cells Impairs Hematopoiesis and Disturbs Erythrocyte Maturation

Numerous studies highlight the potential benefits potentials of supplemental cartilage oligomeric matrix protein-angiopoietin-1 (COMP-Ang1) through improved angiogenic effects. However, our recent findings show that excessive overexpression of COMP-Ang1 induces an impaired bone marrow (BM) microenvi...

Descripción completa

Detalles Bibliográficos
Autores principales:	Sim, Hyun-Jaung, Kim, Min-Hye, Bhattarai, Govinda, Hwang, Jae-Won, So, Han-Sol, Poudel, Sher Bahadur, Cho, Eui-Sic, Kook, Sung-Ho, Lee, Jeong-Chae
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Korean Society for Molecular and Cellular Biology 2021
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112173/ https://www.ncbi.nlm.nih.gov/pubmed/33935045 http://dx.doi.org/10.14348/molcells.2021.2155

Ejemplares similares

Local and Systemic Overexpression of COMP-Ang1 Induces Ang1/Tie2-Related Thrombocytopenia and SDF-1/CXCR4-Dependent Anemia
por: Sim, Hyun-Jaung, et al.
Publicado: (2022)

Osteoblastic Wls Ablation Protects Mice from Total Body Irradiation-Induced Impairments in Hematopoiesis and Bone Marrow Microenvironment
por: Sim, Hyun-Jaung, et al.
Publicado: (2023)

Biopotentials of Collagen Scaffold Impregnated with Plant-Cell-Derived Epidermal Growth Factor in Defective Bone Healing
por: Poudel, Sher Bahadur, et al.
Publicado: (2023)

The Long-lasting Radioprotective Effect of Caffeic Acid in Mice Exposed to Total Body Irradiation by Modulating Reactive Oxygen Species Generation and Hematopoietic Stem Cell Senescence-Accompanied Long-term Residual Bone Marrow Injury
por: Sim, Hyun-Jaung, et al.
Publicado: (2019)

COMP-Angiopoietin-1 accelerates muscle regeneration through N-cadherin activation
por: Youn, Seock-Won, et al.
Publicado: (2018)

Supplemental Ferulic Acid Inhibits Total Body Irradiation-Mediated Bone Marrow Damage, Bone Mass Loss, Stem Cell Senescence, and Hematopoietic Defect in Mice by Enhancing Antioxidant Defense Systems
por: Wagle, Sajeev, et al.
Publicado: (2021)

Designed angiopoietin-1 variant, COMP-angiopoietin-1, rescues erectile function through healthy cavernous angiogenesis in a hypercholesterolemic mouse
por: Ryu, Ji-Kan, et al.
Publicado: (2015)

Maternal exposure to fine particulate matter during pregnancy induces progressive senescence of hematopoietic stem cells under preferential impairment of the bone marrow microenvironment and aids development of myeloproliferative disease
por: Bhattarai, Govinda, et al.
Publicado: (2019)

Prion infection modulates hematopoietic stem/progenitor cell fate through cell-autonomous and non-autonomous mechanisms
por: Sim, Hyun-Jaung, et al.
Publicado: (2023)

COMP-Angiopoietin-1 Promotes Cavernous Angiogenesis in a Type 2 Diabetic Rat Model
por: Kim, Sun-Ouck, et al.
Publicado: (2013)

Astaxanthin Protects against Hyperglycemia-Induced Oxidative and Inflammatory Damage to Bone Marrow and to Bone Marrow-Retained Stem Cells and Restores Normal Hematopoiesis in Streptozotocin-Induced Diabetic Mice
por: Bhattarai, Govinda, et al.
Publicado: (2022)

COMP-Angiopoietin-1 Recovers Molecular Biomarkers of Neuropathy and Improves Vascularisation in Sciatic Nerve of ob/ob Mice
por: Kosacka, Joanna, et al.
Publicado: (2012)

COMP-Angiopoietin1 Potentiates the Effects of Bone Morphogenic Protein-2 on Ischemic Necrosis of the Femoral Head in Rats
por: Zhou, Lu, et al.
Publicado: (2014)

COMP-angiopoietin-1 ameliorates inflammation-induced lymphangiogenesis in dextran sulfate sodium (DSS)-induced colitis model
por: Lee, Ae Sin, et al.
Publicado: (2018)

Tubular Overexpression of Angiopoietin-1 Attenuates Renal Fibrosis
por: Singh, Sudhir, et al.
Publicado: (2016)

Vascular Endothelial Growth Factor and Angiopoietin-1 Stimulate Postnatal Hematopoiesis by Recruitment of Vasculogenic and Hematopoietic Stem Cells
por: Hattori, Koichi, et al.
Publicado: (2001)

Overexpression of angiopoietin-1 reduces doxorubicin-induced apoptosis in cardiomyocytes
por: Ren, Danyang, et al.
Publicado: (2012)

Periodontal Ligament-Mimetic Fibrous Scaffolds Regulate YAP-Associated Fibroblast Behaviors and Promote Regeneration of Periodontal Defect in Relation to the Scaffold Topography
por: Kim, Jeong In, et al.
Publicado: (2022)

Correction to “Periodontal Ligament-Mimetic Fibrous Scaffolds Regulate YAP-Associated Fibroblast Behaviors and Promote Regeneration of Periodontal Defect in Relation to the Scaffold Topography”
por: Kim, Jeong In, et al.
Publicado: (2023)

The Angiopoietin-1 Variant COMP-Ang1 Enhances BMP2-Induced Bone Regeneration with Recruiting Pericytes in Critical Sized Calvarial Defects
por: Choi, Hyuck, et al.
Publicado: (2015)

COMP-angiopoietin-1 mitigates changes in lipid droplet size, macrophage infiltration of adipose tissue and renal inflammation in streptozotocin-induced diabetic mice
por: Jung, Yu Jin, et al.
Publicado: (2017)

GENE CONTROL OF HEMATOPOIESIS : I. ERYTHROCYTE MOSAICISM AND PERMANENT IMMUNOLOGICAL TOLERANCE IN ALLOPHENIC MICE
por: Mintz, Beatrice, et al.
Publicado: (1969)

Astaxanthin Inhibits Diabetes-Triggered Periodontal Destruction, Ameliorates Oxidative Complications in STZ-Injected Mice, and Recovers Nrf2-Dependent Antioxidant System
por: Bhattarai, Govinda, et al.
Publicado: (2021)

DAP12 Overexpression Induces Osteopenia and Impaired Early Hematopoiesis
por: Despars, Geneviève, et al.
Publicado: (2013)

Prolonged Intradialytic Hypoxemia Is Associated With Functional Disturbances in Erythrocytes
por: Hartzell, Susan, et al.
Publicado: (2021)

CompTIA security+
por: Barrett, Diane, et al.
Publicado: (2009)

CompTIA Server+
por: Brooks, Charles J
Publicado: (2006)

CompTIA network+
por: Harwood, Mike
Publicado: (2009)

CompTIA A+.
por: Brooks, Charles J
Publicado: (2007)

Anti-angiogenic Targets: Angiopoietin and Angiopoietin Receptors
por: Kiss, Elina A., et al.
Publicado: (2019)

Association of serum angiopoietin-1, angiopoietin-2 and angiopoietin-2 to angiopoietin-1 ratio with heart failure in patients with acute myocardial infarction
por: CHEN, SHAOMIN, et al.
Publicado: (2013)

Aggrecan and COMP Improve Periosteal Chondrogenesis by Delaying Chondrocyte Hypertrophic Maturation
por: Caron, Marjolein M. J., et al.
Publicado: (2020)

Stage-dependent angiopoietin-Tie2 and nitric oxide signaling of erythrocytes in response to surgical trauma in head and neck cancer
por: Wu, Hsiang-Ling, et al.
Publicado: (2020)

Overexpression of wild-type or mutants forms of CEBPA alter normal human hematopoiesis
por: Quintana-Bustamante, Oscar, et al.
Publicado: (2012)

EVI1 overexpression reprograms hematopoiesis via upregulation of Spi1 transcription
por: Ayoub, Edward, et al.
Publicado: (2018)

Review of W/lines + COMP
Publicado: (1975)

CompTIA A+ certification
por: Meyers, Michael, et al.
Publicado: (2010)

Cooperation of Angiopoietin-2 and Angiopoietin-4 in Schlemm's Canal Maintenance
por: Kapiainen, Emmi, et al.
Publicado: (2022)

Inflammatory myo-fibroblastic tumor of appendix: A rare clinical entity
por: Baral, Suman, et al.
Publicado: (2021)

Angiopoietin-2 and Angiopoietin-2/Angiopoietin-1 Ratio as Indicators of Potential Severity of Plasmodium vivax Malaria in Patients with Thrombocytopenia
por: Gomes, Luciano Teixeira, et al.
Publicado: (2014)

Cannot write session to /tmp/vufind_sessions/sess_ghqihutvdssvsgg0i7135aql56