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Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest comp...
Autores principales: | , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Hindawi
2021
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112196/ https://www.ncbi.nlm.nih.gov/pubmed/34055034 http://dx.doi.org/10.1155/2021/5527271 |
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author | Helwan, Abdulkader Ma'aitah, Mohammad Khaleel Sallam Hamdan, Hani Ozsahin, Dilber Uzun Tuncyurek, Ozum |
author_facet | Helwan, Abdulkader Ma'aitah, Mohammad Khaleel Sallam Hamdan, Hani Ozsahin, Dilber Uzun Tuncyurek, Ozum |
author_sort | Helwan, Abdulkader |
collection | PubMed |
description | The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest computed tomography (CT) has been an efficient tool to diagnose COVID-19 as it is directly affecting the lungs. In this paper, we investigate the application of pre-trained models in diagnosing patients who are positive for COVID-19 and differentiating it from normal patients, who tested negative for coronavirus. The study aims to compare the generalization capabilities of deep learning models with two thoracic radiologists in diagnosing COVID-19 chest CT images. A dataset of 3000 images was obtained from the Near East Hospital, Cyprus, and used to train and to test the three employed pre-trained models. In a test set of 250 images used to evaluate the deep neural networks and the radiologists, it was found that deep networks (ResNet-18, ResNet-50, and DenseNet-201) can outperform the radiologists in terms of higher accuracy (97.8%), sensitivity (98.1%), specificity (97.3%), precision (98.4%), and F1-score (198.25%), in classifying COVID-19 images. |
format | Online Article Text |
id | pubmed-8112196 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Hindawi |
record_format | MEDLINE/PubMed |
spelling | pubmed-81121962021-05-27 Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 Helwan, Abdulkader Ma'aitah, Mohammad Khaleel Sallam Hamdan, Hani Ozsahin, Dilber Uzun Tuncyurek, Ozum Comput Math Methods Med Research Article The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest computed tomography (CT) has been an efficient tool to diagnose COVID-19 as it is directly affecting the lungs. In this paper, we investigate the application of pre-trained models in diagnosing patients who are positive for COVID-19 and differentiating it from normal patients, who tested negative for coronavirus. The study aims to compare the generalization capabilities of deep learning models with two thoracic radiologists in diagnosing COVID-19 chest CT images. A dataset of 3000 images was obtained from the Near East Hospital, Cyprus, and used to train and to test the three employed pre-trained models. In a test set of 250 images used to evaluate the deep neural networks and the radiologists, it was found that deep networks (ResNet-18, ResNet-50, and DenseNet-201) can outperform the radiologists in terms of higher accuracy (97.8%), sensitivity (98.1%), specificity (97.3%), precision (98.4%), and F1-score (198.25%), in classifying COVID-19 images. Hindawi 2021-05-10 /pmc/articles/PMC8112196/ /pubmed/34055034 http://dx.doi.org/10.1155/2021/5527271 Text en Copyright © 2021 Abdulkader Helwan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. |
spellingShingle | Research Article Helwan, Abdulkader Ma'aitah, Mohammad Khaleel Sallam Hamdan, Hani Ozsahin, Dilber Uzun Tuncyurek, Ozum Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 |
title | Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 |
title_full | Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 |
title_fullStr | Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 |
title_full_unstemmed | Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 |
title_short | Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 |
title_sort | radiologists versus deep convolutional neural networks: a comparative study for diagnosing covid-19 |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112196/ https://www.ncbi.nlm.nih.gov/pubmed/34055034 http://dx.doi.org/10.1155/2021/5527271 |
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