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Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19

The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest comp...

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Autores principales: Helwan, Abdulkader, Ma'aitah, Mohammad Khaleel Sallam, Hamdan, Hani, Ozsahin, Dilber Uzun, Tuncyurek, Ozum
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Hindawi 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112196/
https://www.ncbi.nlm.nih.gov/pubmed/34055034
http://dx.doi.org/10.1155/2021/5527271
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author Helwan, Abdulkader
Ma'aitah, Mohammad Khaleel Sallam
Hamdan, Hani
Ozsahin, Dilber Uzun
Tuncyurek, Ozum
author_facet Helwan, Abdulkader
Ma'aitah, Mohammad Khaleel Sallam
Hamdan, Hani
Ozsahin, Dilber Uzun
Tuncyurek, Ozum
author_sort Helwan, Abdulkader
collection PubMed
description The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest computed tomography (CT) has been an efficient tool to diagnose COVID-19 as it is directly affecting the lungs. In this paper, we investigate the application of pre-trained models in diagnosing patients who are positive for COVID-19 and differentiating it from normal patients, who tested negative for coronavirus. The study aims to compare the generalization capabilities of deep learning models with two thoracic radiologists in diagnosing COVID-19 chest CT images. A dataset of 3000 images was obtained from the Near East Hospital, Cyprus, and used to train and to test the three employed pre-trained models. In a test set of 250 images used to evaluate the deep neural networks and the radiologists, it was found that deep networks (ResNet-18, ResNet-50, and DenseNet-201) can outperform the radiologists in terms of higher accuracy (97.8%), sensitivity (98.1%), specificity (97.3%), precision (98.4%), and F1-score (198.25%), in classifying COVID-19 images.
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spelling pubmed-81121962021-05-27 Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19 Helwan, Abdulkader Ma'aitah, Mohammad Khaleel Sallam Hamdan, Hani Ozsahin, Dilber Uzun Tuncyurek, Ozum Comput Math Methods Med Research Article The reverse transcriptase polymerase chain reaction (RT-PCR) is still the routinely used test for the diagnosis of SARS-CoV-2 (COVID-19). However, according to several reports, RT-PCR showed a low sensitivity and multiple tests may be required to rule out false negative results. Recently, chest computed tomography (CT) has been an efficient tool to diagnose COVID-19 as it is directly affecting the lungs. In this paper, we investigate the application of pre-trained models in diagnosing patients who are positive for COVID-19 and differentiating it from normal patients, who tested negative for coronavirus. The study aims to compare the generalization capabilities of deep learning models with two thoracic radiologists in diagnosing COVID-19 chest CT images. A dataset of 3000 images was obtained from the Near East Hospital, Cyprus, and used to train and to test the three employed pre-trained models. In a test set of 250 images used to evaluate the deep neural networks and the radiologists, it was found that deep networks (ResNet-18, ResNet-50, and DenseNet-201) can outperform the radiologists in terms of higher accuracy (97.8%), sensitivity (98.1%), specificity (97.3%), precision (98.4%), and F1-score (198.25%), in classifying COVID-19 images. Hindawi 2021-05-10 /pmc/articles/PMC8112196/ /pubmed/34055034 http://dx.doi.org/10.1155/2021/5527271 Text en Copyright © 2021 Abdulkader Helwan et al. https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Research Article
Helwan, Abdulkader
Ma'aitah, Mohammad Khaleel Sallam
Hamdan, Hani
Ozsahin, Dilber Uzun
Tuncyurek, Ozum
Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
title Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
title_full Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
title_fullStr Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
title_full_unstemmed Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
title_short Radiologists versus Deep Convolutional Neural Networks: A Comparative Study for Diagnosing COVID-19
title_sort radiologists versus deep convolutional neural networks: a comparative study for diagnosing covid-19
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112196/
https://www.ncbi.nlm.nih.gov/pubmed/34055034
http://dx.doi.org/10.1155/2021/5527271
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