Cargando…

Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study

INTRODUCTION: Acute mesenteric ischemia (AMI) is the sudden onset of small intestinal hypoperfusion, which can be due to reduction or cessation of arterial inflow. It can be embolic or thrombotic. AMI is a potentially fatal vascular emergency, with overall mortality of 60%–80%. The present study was...

Descripción completa

Detalles Bibliográficos
Autores principales: Kundan, Meghraj, Chebrolu, Hethu, Muniswamppa, Chetan, Kumar, Niranjan, Chintamani, Varma, Vinayak
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Wolters Kluwer - Medknow 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112362/
https://www.ncbi.nlm.nih.gov/pubmed/34012236
http://dx.doi.org/10.4103/njs.NJS_54_20
_version_ 1783690675163758592
author Kundan, Meghraj
Chebrolu, Hethu
Muniswamppa, Chetan
Kumar, Niranjan
Chintamani,
Varma, Vinayak
author_facet Kundan, Meghraj
Chebrolu, Hethu
Muniswamppa, Chetan
Kumar, Niranjan
Chintamani,
Varma, Vinayak
author_sort Kundan, Meghraj
collection PubMed
description INTRODUCTION: Acute mesenteric ischemia (AMI) is the sudden onset of small intestinal hypoperfusion, which can be due to reduction or cessation of arterial inflow. It can be embolic or thrombotic. AMI is a potentially fatal vascular emergency, with overall mortality of 60%–80%. The present study was designed to study presentation, risk factors, and various outcomes of AMI patients, who were treated in the tertiary hospital. METHODOLOGY: All patients with features suggestive of AMI were taken in study. All patients underwent explorative laparotomy with exteriorization of bowel after initial resuscitation. Postoperatively, refeeding enteroclysis was done. OBSERVATION AND RESULTS: The total mortality rate was 62.50%. In patients with functional bowel length of 1 foot, 90.90% patients died. In patients with functional bowel length of 5–6 feet, only 12.50% died. It was observed that the mortality rate was more in the age group of 50–59 years with functional bowel length of 1 foot or <1 foot. Refeeding enteroclysis is an effective technique to use distal bowel. Contrast-enhanced computed tomography of the abdomen more suggestive of this pathology. CONCLUSIONS: A strong clinical suspicion and an aggressive approach should be considered in dealing with this condition because the outcome mainly depends on rapid diagnosis and treatment. With understanding of the pathogenesis of AMI and the better utilization of available radiological investigations, an improved outcome can be achieved. Mortality rates with refeeding enteroclysis are comparable with that of bowel anastomosis. This condition needs future research.
format Online
Article
Text
id pubmed-8112362
institution National Center for Biotechnology Information
language English
publishDate 2021
publisher Wolters Kluwer - Medknow
record_format MEDLINE/PubMed
spelling pubmed-81123622021-05-18 Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study Kundan, Meghraj Chebrolu, Hethu Muniswamppa, Chetan Kumar, Niranjan Chintamani, Varma, Vinayak Niger J Surg Original Article INTRODUCTION: Acute mesenteric ischemia (AMI) is the sudden onset of small intestinal hypoperfusion, which can be due to reduction or cessation of arterial inflow. It can be embolic or thrombotic. AMI is a potentially fatal vascular emergency, with overall mortality of 60%–80%. The present study was designed to study presentation, risk factors, and various outcomes of AMI patients, who were treated in the tertiary hospital. METHODOLOGY: All patients with features suggestive of AMI were taken in study. All patients underwent explorative laparotomy with exteriorization of bowel after initial resuscitation. Postoperatively, refeeding enteroclysis was done. OBSERVATION AND RESULTS: The total mortality rate was 62.50%. In patients with functional bowel length of 1 foot, 90.90% patients died. In patients with functional bowel length of 5–6 feet, only 12.50% died. It was observed that the mortality rate was more in the age group of 50–59 years with functional bowel length of 1 foot or <1 foot. Refeeding enteroclysis is an effective technique to use distal bowel. Contrast-enhanced computed tomography of the abdomen more suggestive of this pathology. CONCLUSIONS: A strong clinical suspicion and an aggressive approach should be considered in dealing with this condition because the outcome mainly depends on rapid diagnosis and treatment. With understanding of the pathogenesis of AMI and the better utilization of available radiological investigations, an improved outcome can be achieved. Mortality rates with refeeding enteroclysis are comparable with that of bowel anastomosis. This condition needs future research. Wolters Kluwer - Medknow 2021 2021-03-09 /pmc/articles/PMC8112362/ /pubmed/34012236 http://dx.doi.org/10.4103/njs.NJS_54_20 Text en Copyright: © 2021 Nigerian Journal of Surgery https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open access journal, and articles are distributed under the terms of the Creative Commons Attribution-NonCommercial-ShareAlike 4.0 License, which allows others to remix, tweak, and build upon the work non-commercially, as long as appropriate credit is given and the new creations are licensed under the identical terms.
spellingShingle Original Article
Kundan, Meghraj
Chebrolu, Hethu
Muniswamppa, Chetan
Kumar, Niranjan
Chintamani,
Varma, Vinayak
Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study
title Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study
title_full Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study
title_fullStr Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study
title_full_unstemmed Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study
title_short Outcomes of Management of Patients with Acute Mesenteric Ischemia: A Prospective Study
title_sort outcomes of management of patients with acute mesenteric ischemia: a prospective study
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112362/
https://www.ncbi.nlm.nih.gov/pubmed/34012236
http://dx.doi.org/10.4103/njs.NJS_54_20
work_keys_str_mv AT kundanmeghraj outcomesofmanagementofpatientswithacutemesentericischemiaaprospectivestudy
AT chebroluhethu outcomesofmanagementofpatientswithacutemesentericischemiaaprospectivestudy
AT muniswamppachetan outcomesofmanagementofpatientswithacutemesentericischemiaaprospectivestudy
AT kumarniranjan outcomesofmanagementofpatientswithacutemesentericischemiaaprospectivestudy
AT chintamani outcomesofmanagementofpatientswithacutemesentericischemiaaprospectivestudy
AT varmavinayak outcomesofmanagementofpatientswithacutemesentericischemiaaprospectivestudy