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Pan-cancer landscape of CD274 (PD-L1) copy number changes in 244 584 patient samples and the correlation with PD-L1 protein expression

INTRODUCTION: Several studies have shown clinical outcomes data that support the use of CD274 (PD-L1) copy-number (CN) gains and/or losses as a biomarker for immune checkpoint inhibitor (ICPI). Here, we present the landscape of CD274 CN changes across a large cohort of solid tumor cases and correlat...

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Detalles Bibliográficos
Autores principales:	Huang, Richard S.P., Murugesan, Karthikeyan, Montesion, Meagan, Pavlick, Dean C., Mata, Douglas A., Hiemenz, Matthew C., Decker, Brennan, Frampton, Garrett, Albacker, Lee A., Ross, Jeffrey S.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	BMJ Publishing Group 2021
Materias:	Immunotherapy Biomarkers
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112409/ https://www.ncbi.nlm.nih.gov/pubmed/33972391 http://dx.doi.org/10.1136/jitc-2021-002680

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