Cargando…

SARS-CoV-2 in patients with cancer: possible role of mimicry of human molecules by viral proteins and the resulting anti-cancer immunity

A few reports suggest that molecular mimicry can have a role in determining the more severe and deadly forms of COVID-19, inducing endothelial damage, disseminated intravascular coagulation, and multiorgan failure. Heat shock proteins/molecular chaperones can be involved in these molecular mimicry p...

Descripción completa

Detalles Bibliográficos
Autores principales:	Burgio, Stefano, Conway de Macario, Everly, Macario, Alberto JL, Cappello, Francesco
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Netherlands 2021
Materias:	Mini Review
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112475/ https://www.ncbi.nlm.nih.gov/pubmed/33977496 http://dx.doi.org/10.1007/s12192-021-01211-7

Ejemplares similares

Unexpected tumor reduction in metastatic colorectal cancer patients during SARS-Cov-2 infection: effect of ACE-2 expression on tumor cells or molecular mimicry phenomena? Two not mutually exclusive hypotheses
por: Cappello, Francesco, et al.
Publicado: (2021)

Does SARS-CoV-2 Trigger Stress-Induced Autoimmunity by Molecular Mimicry? A Hypothesis
por: Cappello, Francesco, et al.
Publicado: (2020)

Human molecular chaperones share with SARS-CoV-2 antigenic epitopes potentially capable of eliciting autoimmunity against endothelial cells: possible role of molecular mimicry in COVID-19
por: Marino Gammazza, Antonella, et al.
Publicado: (2020)

Molecular mimicry may explain multi-organ damage in COVID-19
por: Angileri, Francesca, et al.
Publicado: (2020)

hsp70 genes in the human genome: Conservation and differentiation patterns predict a wide array of overlapping and specialized functions
por: Brocchieri, Luciano, et al.
Publicado: (2008)

Chlamydia trachomatis Infection and Anti-Hsp60 Immunity: The Two Sides of the Coin
por: Cappello, Francesco, et al.
Publicado: (2009)

Histopathology of Skeletal Muscle in a Distal Motor Neuropathy Associated with a Mutant CCT5 Subunit: Clues for Future Developments to Improve Differential Diagnosis and Personalized Therapy
por: Scalia, Federica, et al.
Publicado: (2023)

Chaperonin genes on the rise: new divergent classes and intense duplication in human and other vertebrate genomes
por: Mukherjee, Krishanu, et al.
Publicado: (2010)

The chaperone system in cancer therapies: Hsp90
por: Basset, Charbel A., et al.
Publicado: (2023)

Myelin Pathology: Involvement of Molecular Chaperones and the Promise of Chaperonotherapy
por: Scalia, Federica, et al.
Publicado: (2019)

The Role of Molecular Chaperones in Virus Infection and Implications for Understanding and Treating COVID-19
por: Paladino, Letizia, et al.
Publicado: (2020)

Editorial: Pathologic Conditions of the Human Nervous and Muscular Systems Associated with Mutant Chaperones: Molecular and Mechanistic Aspects
por: Macario, Alberto J. L., et al.
Publicado: (2018)

Missense Mutations of Human Hsp60: A Computational Analysis to Unveil Their Pathological Significance
por: Vitale, Alessandra Maria, et al.
Publicado: (2020)

The Chaperone System in Breast Cancer: Roles and Therapeutic Prospects of the Molecular Chaperones Hsp27, Hsp60, Hsp70, and Hsp90
por: Alberti, Giusi, et al.
Publicado: (2022)

MATURATION OF THE IMMUNE RESPONSE IN VITRO : FOCAL FLUCTUATION AND CHANGES IN AFFINITY OF ANTI-β-D-GALACTOSIDASE ACTIVATING ANTIBODY
por: Macario, Alberto J. L., et al.
Publicado: (1972)

Prokaryotic Chaperonins as Experimental Models for Elucidating Structure-Function Abnormalities of Human Pathogenic Mutant Counterparts
por: Conway de Macario, Everly, et al.
Publicado: (2017)

HSP60 activity on human bronchial epithelial cells
por: Sangiorgi, Claudia, et al.
Publicado: (2017)

Circulating Molecular Chaperones in Subjects with Amnestic Mild Cognitive Impairment and Alzheimer’s Disease: Data from the Zabùt Aging Project
por: Marino Gammazza, Antonella, et al.
Publicado: (2022)

Bridging human chaperonopathies and microbial chaperonins
por: Conway de Macario, Everly, et al.
Publicado: (2019)

Hsp60 Is Actively Secreted by Human Tumor Cells
por: Merendino, Anna M., et al.
Publicado: (2010)

Quantitative analysis of the impact of a human pathogenic mutation on the CCT5 chaperonin subunit using a proxy archaeal ortholog()
por: Spigolon, Dario, et al.
Publicado: (2017)

The Odyssey of Hsp60 from Tumor Cells to Other Destinations Includes Plasma Membrane-Associated Stages and Golgi and Exosomal Protein-Trafficking Modalities
por: Campanella, Claudia, et al.
Publicado: (2012)

Extracellular Vesicle-Mediated Cell–Cell Communication in the Nervous System: Focus on Neurological Diseases
por: Caruso Bavisotto, Celeste, et al.
Publicado: (2019)

Molecular Pathways Implicated in Radioresistance of Glioblastoma Multiforme: What Is the Role of Extracellular Vesicles?
por: Burko, Pavel, et al.
Publicado: (2023)

Lipid chaperones and associated diseases: a group of chaperonopathies defining a new nosological entity with implications for medical research and practice
por: D’Anneo, Antonella, et al.
Publicado: (2020)

The histone deacetylase inhibitor SAHA induces HSP60 nitration and its extracellular release by exosomal vesicles in human lung-derived carcinoma cells
por: Campanella, Claudia, et al.
Publicado: (2015)

Chaperonin of Group I: Oligomeric Spectrum and Biochemical and Biological Implications
por: Vilasi, Silvia, et al.
Publicado: (2018)

Immunomorphological Patterns of Chaperone System Components in Rare Thyroid Tumors with Promise as Biomarkers for Differential Diagnosis and Providing Clues on Molecular Mechanisms of Carcinogenesis
por: Paladino, Letizia, et al.
Publicado: (2023)

Skeletal muscle Heat shock protein 60 increases after endurance training and induces peroxisome proliferator-activated receptor gamma coactivator 1 α1 expression
por: Barone, Rosario, et al.
Publicado: (2016)

Structural and Dynamic Disturbances Revealed by Molecular Dynamics Simulations Predict the Impact on Function of CCT5 Chaperonin Mutations Associated with Rare Severe Distal Neuropathies
por: Scalia, Federica, et al.
Publicado: (2023)

Molecular Chaperones and Thyroid Cancer
por: Paladino, Letizia, et al.
Publicado: (2021)

Hsp60 as a Novel Target in IBD Management: A Prospect
por: Cappello, Francesco, et al.
Publicado: (2019)

A human CCT5 gene mutation causing distal neuropathy impairs hexadecamer assembly in an archaeal model
por: Min, Wonki, et al.
Publicado: (2014)

Hsp60 Post-translational Modifications: Functional and Pathological Consequences
por: Caruso Bavisotto, Celeste, et al.
Publicado: (2020)

NF-kB Regulation and the Chaperone System Mediate Restorative Effects of the Probiotic Lactobacillus fermentum LF31 in the Small Intestine and Cerebellum of Mice with Ethanol-Induced Damage
por: Paladino, Letizia, et al.
Publicado: (2023)

Exosomal Chaperones and miRNAs in Gliomagenesis: State-of-Art and Theranostics Perspectives
por: Caruso Bavisotto, Celeste, et al.
Publicado: (2018)

Chaperonology: The Third Eye on Brain Gliomas
por: Graziano, Francesca, et al.
Publicado: (2018)

Role of Molecular Chaperones in Carcinogenesis: Mechanism, Diagnosis, and Treatment
por: Conway de Macario, Everly, et al.
Publicado: (2020)

A Novel CCT5 Missense Variant Associated with Early Onset Motor Neuropathy
por: Antona, Vincenzo, et al.
Publicado: (2020)

Angiogenesis and vasculogenic mimicry as therapeutic targets in ovarian cancer
por: Lim, Dansaem, et al.
Publicado: (2020)

Cannot write session to /tmp/vufind_sessions/sess_qr552pq0b3hubbn85e4hl09ip7