Cargando…
Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes
OBJECTIVE: The aim of this study was to investigate prevalence of idiopathic and secondary restless legs syndrome (RLS) according to pregnancy trimester, and its effects on delivery-related outcomes among pregnant women in Japan. METHODS: This was a single-center, prospective observational study. On...
Autores principales: | , , , , , , , , , |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Public Library of Science
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112660/ https://www.ncbi.nlm.nih.gov/pubmed/33974646 http://dx.doi.org/10.1371/journal.pone.0251298 |
_version_ | 1783690712933466112 |
---|---|
author | Yoshimura, Chikara Arima, Hisatomi Amagase, Hironobu Takewaka, Mizuko Nakashima, Kazuko Imaoka, Chikako Miyanaga, Nanami Obama, Hirotsugu Fujita, Masaki Ando, Shin-ichi |
author_facet | Yoshimura, Chikara Arima, Hisatomi Amagase, Hironobu Takewaka, Mizuko Nakashima, Kazuko Imaoka, Chikako Miyanaga, Nanami Obama, Hirotsugu Fujita, Masaki Ando, Shin-ichi |
author_sort | Yoshimura, Chikara |
collection | PubMed |
description | OBJECTIVE: The aim of this study was to investigate prevalence of idiopathic and secondary restless legs syndrome (RLS) according to pregnancy trimester, and its effects on delivery-related outcomes among pregnant women in Japan. METHODS: This was a single-center, prospective observational study. One hundred eighty-two consecutive pregnant women participated in the study from June 2014 to March 2016. Participants were interviewed and examined in the second and third trimesters of pregnancy and 1 month after delivery. At each term, RLS was identified by a research assistant and then specialist in sleep medicine based on the diagnostic criteria of the International Restless Legs Syndrome Study Group. Delivery-related data was collected from medical charts. RLS was classified as idiopathic RLS, which originally existed before the index pregnancy, or secondary RLS, which newly appeared during the index pregnancy. RESULTS: The prevalence of RLS was 4.9% (idiopathic 3.3%, secondary 1.6%) in the second trimester, 5.0% (idiopathic 0.0%, secondary 5.0%) in the third trimester, and 0.6% (idiopathic 0.0%, secondary 0.6%) after delivery. Prolonged labor, emergency Cesarean section, and arrest of labor tended to be more frequent in idiopathic and/or second RLS (all p<0.05). CONCLUSIONS: The prevalence of RLS during pregnancy was 4–5% and decreases after delivery in current Japan. The presence of RLS was associated with an increase in some delivery-related outcomes. Early detection and treatment of RLS during pregnancy may be beneficial to safe delivery for pregnant women. |
format | Online Article Text |
id | pubmed-8112660 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2021 |
publisher | Public Library of Science |
record_format | MEDLINE/PubMed |
spelling | pubmed-81126602021-05-24 Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes Yoshimura, Chikara Arima, Hisatomi Amagase, Hironobu Takewaka, Mizuko Nakashima, Kazuko Imaoka, Chikako Miyanaga, Nanami Obama, Hirotsugu Fujita, Masaki Ando, Shin-ichi PLoS One Research Article OBJECTIVE: The aim of this study was to investigate prevalence of idiopathic and secondary restless legs syndrome (RLS) according to pregnancy trimester, and its effects on delivery-related outcomes among pregnant women in Japan. METHODS: This was a single-center, prospective observational study. One hundred eighty-two consecutive pregnant women participated in the study from June 2014 to March 2016. Participants were interviewed and examined in the second and third trimesters of pregnancy and 1 month after delivery. At each term, RLS was identified by a research assistant and then specialist in sleep medicine based on the diagnostic criteria of the International Restless Legs Syndrome Study Group. Delivery-related data was collected from medical charts. RLS was classified as idiopathic RLS, which originally existed before the index pregnancy, or secondary RLS, which newly appeared during the index pregnancy. RESULTS: The prevalence of RLS was 4.9% (idiopathic 3.3%, secondary 1.6%) in the second trimester, 5.0% (idiopathic 0.0%, secondary 5.0%) in the third trimester, and 0.6% (idiopathic 0.0%, secondary 0.6%) after delivery. Prolonged labor, emergency Cesarean section, and arrest of labor tended to be more frequent in idiopathic and/or second RLS (all p<0.05). CONCLUSIONS: The prevalence of RLS during pregnancy was 4–5% and decreases after delivery in current Japan. The presence of RLS was associated with an increase in some delivery-related outcomes. Early detection and treatment of RLS during pregnancy may be beneficial to safe delivery for pregnant women. Public Library of Science 2021-05-11 /pmc/articles/PMC8112660/ /pubmed/33974646 http://dx.doi.org/10.1371/journal.pone.0251298 Text en © 2021 Yoshimura et al https://creativecommons.org/licenses/by/4.0/This is an open access article distributed under the terms of the Creative Commons Attribution License (https://creativecommons.org/licenses/by/4.0/) , which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are credited. |
spellingShingle | Research Article Yoshimura, Chikara Arima, Hisatomi Amagase, Hironobu Takewaka, Mizuko Nakashima, Kazuko Imaoka, Chikako Miyanaga, Nanami Obama, Hirotsugu Fujita, Masaki Ando, Shin-ichi Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes |
title | Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes |
title_full | Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes |
title_fullStr | Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes |
title_full_unstemmed | Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes |
title_short | Idiopathic and secondary restless legs syndrome during pregnancy in Japan: Prevalence, clinical features and delivery-related outcomes |
title_sort | idiopathic and secondary restless legs syndrome during pregnancy in japan: prevalence, clinical features and delivery-related outcomes |
topic | Research Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112660/ https://www.ncbi.nlm.nih.gov/pubmed/33974646 http://dx.doi.org/10.1371/journal.pone.0251298 |
work_keys_str_mv | AT yoshimurachikara idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT arimahisatomi idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT amagasehironobu idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT takewakamizuko idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT nakashimakazuko idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT imaokachikako idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT miyanagananami idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT obamahirotsugu idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT fujitamasaki idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes AT andoshinichi idiopathicandsecondaryrestlesslegssyndromeduringpregnancyinjapanprevalenceclinicalfeaturesanddeliveryrelatedoutcomes |