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Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study
Background: Numerical dental anomalies, through their phenotypic diversity and etiological complexity, represent a very topical chapter in dental practice. In Romania, there is no recent complex genetic study, regarding supernumerary teeth (ST), as a whole. Patients, Materials and Methods: In this r...
Autores principales: | , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest
2020
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112786/ https://www.ncbi.nlm.nih.gov/pubmed/33817726 http://dx.doi.org/10.47162/RJME.61.3.23 |
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author | Albu, Ştefan-Dimitrie Pavlovici, Romina-Christiana Imre, Marina Ion, George Ţâncu, Ana Maria Cristina Albu, Cristina-Crenguţa |
author_facet | Albu, Ştefan-Dimitrie Pavlovici, Romina-Christiana Imre, Marina Ion, George Ţâncu, Ana Maria Cristina Albu, Cristina-Crenguţa |
author_sort | Albu, Ştefan-Dimitrie |
collection | PubMed |
description | Background: Numerical dental anomalies, through their phenotypic diversity and etiological complexity, represent a very topical chapter in dental practice. In Romania, there is no recent complex genetic study, regarding supernumerary teeth (ST), as a whole. Patients, Materials and Methods: In this research, through the specific genetic study of the phenotypic variability of ST, completed with clinical examinations and paraclinical investigations, to which statistical determinations were added, we performed a complex genetic-clinical and statistical analysis of ST, within a representative group, consisting of 574 patients, who came for specialized dental treatment, between 01/01/2018–05/30/2019, at the private dental offices (Lucky Dental), in Bucharest, Romania. Results: Following this study, it was possible to characterize the phenotypic variability of ST, to analyze the pattern of abnormality genetic transmission in the families of investigated patients, to identify people at risk, and specify the therapeutic conduct of choice, specific to each case. Conclusions: We consider this paper to be of interest for medical practice by bringing new, recent data on the current prevalence of non-syndromic ST, their clinical phenotypes, and the specifics of their genetic determinism in the studied population group. |
format | Online Article Text |
id | pubmed-8112786 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2020 |
publisher | Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest |
record_format | MEDLINE/PubMed |
spelling | pubmed-81127862021-06-01 Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study Albu, Ştefan-Dimitrie Pavlovici, Romina-Christiana Imre, Marina Ion, George Ţâncu, Ana Maria Cristina Albu, Cristina-Crenguţa Rom J Morphol Embryol Original Paper Background: Numerical dental anomalies, through their phenotypic diversity and etiological complexity, represent a very topical chapter in dental practice. In Romania, there is no recent complex genetic study, regarding supernumerary teeth (ST), as a whole. Patients, Materials and Methods: In this research, through the specific genetic study of the phenotypic variability of ST, completed with clinical examinations and paraclinical investigations, to which statistical determinations were added, we performed a complex genetic-clinical and statistical analysis of ST, within a representative group, consisting of 574 patients, who came for specialized dental treatment, between 01/01/2018–05/30/2019, at the private dental offices (Lucky Dental), in Bucharest, Romania. Results: Following this study, it was possible to characterize the phenotypic variability of ST, to analyze the pattern of abnormality genetic transmission in the families of investigated patients, to identify people at risk, and specify the therapeutic conduct of choice, specific to each case. Conclusions: We consider this paper to be of interest for medical practice by bringing new, recent data on the current prevalence of non-syndromic ST, their clinical phenotypes, and the specifics of their genetic determinism in the studied population group. Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest 2020 2021-03-31 /pmc/articles/PMC8112786/ /pubmed/33817726 http://dx.doi.org/10.47162/RJME.61.3.23 Text en Copyright © 2020, Academy of Medical Sciences, Romanian Academy Publishing House, Bucharest https://creativecommons.org/licenses/by-nc-sa/4.0/This is an open-access article distributed under the terms of a Creative Commons Attribution-NonCommercial-ShareAlike 4.0 International Public License, which permits unrestricted use, adaptation, distribution and reproduction in any medium, non-commercially, provided the new creations are licensed under identical terms as the original work and the original work is properly cited. |
spellingShingle | Original Paper Albu, Ştefan-Dimitrie Pavlovici, Romina-Christiana Imre, Marina Ion, George Ţâncu, Ana Maria Cristina Albu, Cristina-Crenguţa Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
title | Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
title_full | Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
title_fullStr | Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
title_full_unstemmed | Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
title_short | Phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
title_sort | phenotypic heterogeneity of non-syndromic supernumerary teeth: genetic study |
topic | Original Paper |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112786/ https://www.ncbi.nlm.nih.gov/pubmed/33817726 http://dx.doi.org/10.47162/RJME.61.3.23 |
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