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Triglyceride Deposit Cardiomyovasculopathy with Massive Myocardial Triglyceride which Was Proven Using Proton-magnetic Resonance Spectroscopy

The patient was a 73-year-old man with a history of hypertension, diabetes mellitus, dyslipidemia, rheumatoid arthritis, repeated percutaneous coronary intervention and percutaneous peripheral intervention procedures. He was frequently admitted to our hospital for congestive heart failure with ortho...

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Detalles Bibliográficos
Autores principales: Sai, Eiryu, Shimada, Kazunori, Aikawa, Tatsuro, Aoshima, Chihiro, Takamura, Kazuhisa, Hiki, Makoto, Yokoyama, Takayuki, Miyazaki, Tetsuro, Fujmoto, Shinichiro, Konishi, Hakuoh, Hirano, Ken-ichi, Daida, Hiroyuki, Minamino, Tohru
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Japanese Society of Internal Medicine 2020
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8112966/
https://www.ncbi.nlm.nih.gov/pubmed/33162485
http://dx.doi.org/10.2169/internalmedicine.6126-20
Descripción
Sumario:The patient was a 73-year-old man with a history of hypertension, diabetes mellitus, dyslipidemia, rheumatoid arthritis, repeated percutaneous coronary intervention and percutaneous peripheral intervention procedures. He was frequently admitted to our hospital for congestive heart failure with orthopnea. The myocardial washout rate of iodine-123-β-methyl iodophenyl-pentadecanoic acid was defective on scintigraphy. He was diagnosed with triglyceride deposit cardiomyovasculopathy (TGCV). Proton magnetic resonance spectroscopy ((1)H-MRS) indicated the level of myocardial triglyceride (TG) content to be extremely high (4.92%). This is the first report to confirm a massive accumulation of TG in the myocardium of a patient with TGCV using (1)H-MRS noninvasively.