Methods of Synthesis and Antiviral Activity of New 4-Alkyl-3-Nitro-1,4-Dihydroazolo[5,1-c][1,2,4]Triazin-4-ols

[Image: see text] An azo coupling reaction of α-nitro ketones with 5-diazoazoles was used to obtain 4-alkyl-3-nitro-1,4-dihydroazolo[5,1-с][1,2,4]triazines, which were characterized with respect to their antiviral activity against influenza and Coxsackie B3 viruses. SUPPLEMENTARY INFORMATION: The on...

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Detalles Bibliográficos
Autores principales: Drokin, Roman A., Tiufiakov, Dmitrii V., Voinkov, Egor K., Slepukhin, Pavel A., Ulomsky, Evgeny N., Esaulkova, Yana L., Volobueva, Alexandrina S., Lantseva, Kristina S., Misyurina, Mariya A., Zarubaev, Vladimir V., Rusinov, Vladimir L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer US 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113020/
https://www.ncbi.nlm.nih.gov/pubmed/33994554
http://dx.doi.org/10.1007/s10593-021-02926-2
Descripción
Sumario:[Image: see text] An azo coupling reaction of α-nitro ketones with 5-diazoazoles was used to obtain 4-alkyl-3-nitro-1,4-dihydroazolo[5,1-с][1,2,4]triazines, which were characterized with respect to their antiviral activity against influenza and Coxsackie B3 viruses. SUPPLEMENTARY INFORMATION: The online version contains supplementary material available at 10.1007/s10593-021-02926-2.

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