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Lack of the antioxidant enzyme methionine sulfoxide reductase A in mice impairs RPE phagocytosis and causes photoreceptor cone dysfunction

Methionine sulfoxide reductase A (MsrA) is a widely expressed antioxidant enzyme that counteracts oxidative protein damage and contributes to protein regulation by reversing oxidation of protein methionine residues. In retinal pigment epithelial (RPE) cells in culture, MsrA overexpression increases...

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Detalles Bibliográficos
Autores principales: Mazzoni, Francesca, Dun, Ying, Vargas, Jade A., Nandrot, Emeline F., Finnemann, Silvia C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Elsevier 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113033/
https://www.ncbi.nlm.nih.gov/pubmed/33674251
http://dx.doi.org/10.1016/j.redox.2021.101918