Cargando…
Lack of the antioxidant enzyme methionine sulfoxide reductase A in mice impairs RPE phagocytosis and causes photoreceptor cone dysfunction
Methionine sulfoxide reductase A (MsrA) is a widely expressed antioxidant enzyme that counteracts oxidative protein damage and contributes to protein regulation by reversing oxidation of protein methionine residues. In retinal pigment epithelial (RPE) cells in culture, MsrA overexpression increases...
Autores principales: | Mazzoni, Francesca, Dun, Ying, Vargas, Jade A., Nandrot, Emeline F., Finnemann, Silvia C. |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Elsevier
2021
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113033/ https://www.ncbi.nlm.nih.gov/pubmed/33674251 http://dx.doi.org/10.1016/j.redox.2021.101918 |
Ejemplares similares
-
Probing Photoreceptor Outer Segment Phagocytosis by the RPE In Vivo: Models and Methodologies
por: Vargas, Jade A., et al.
Publicado: (2022) -
Methionine Sulfoxide Reductases of Archaea
por: Maupin-Furlow, Julie A.
Publicado: (2018) -
Loss of Synchronized Retinal Phagocytosis and Age-related Blindness in Mice Lacking αvβ5 Integrin
por: Nandrot, Emeline F., et al.
Publicado: (2004) -
Selenium and the Methionine Sulfoxide Reductase System
por: Oien, Derek B., et al.
Publicado: (2009) -
Identification of Aeromonas hydrophila Genes Preferentially Expressed after Phagocytosis by Tetrahymena and Involvement of Methionine Sulfoxide Reductases
por: Pang, Maoda, et al.
Publicado: (2016)