Cargando…

Evaluation of [(18)F]F-DPA as a target for TSPO in head and neck cancer under normal conditions and after radiotherapy

BACKGROUND: Many malignant tumours have increased TSPO expression, which has been related to a poor prognosis. TSPO-PET tracers have not comprehensively been evaluated in peripherally located tumours. This study aimed to evaluate whether N,N-diethyl-2-(2-(4-([(18)F]fluoro)phenyl)-5,7-dimethylpyrazol...

Descripción completa

Detalles Bibliográficos
Autores principales:	Tuominen, Sanni, Keller, Thomas, Petruk, Nataliia, López-Picón, Francisco, Eichin, Dominik, Löyttyniemi, Eliisa, Verhassel, Alejandra, Rajander, Johan, Sandholm, Jouko, Tuomela, Johanna, Grönroos, Tove J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Springer Berlin Heidelberg 2020
Materias:	Original Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113193/ https://www.ncbi.nlm.nih.gov/pubmed/33340054 http://dx.doi.org/10.1007/s00259-020-05115-z

Ejemplares similares

Evaluation of [(18)F]F-DPA PET for Detecting Microglial Activation in the Spinal Cord of a Rat Model of Neuropathic Pain
por: Shimochi, Saeka, et al.
Publicado: (2022)

Radiosynthesis and Preclinical Evaluation of [(18)F]F-DPA, A Novel Pyrazolo[1,5a]pyrimidine Acetamide TSPO Radioligand, in Healthy Sprague Dawley Rats
por: Keller, Thomas, et al.
Publicado: (2017)

[(18)F]Fluoride uptake in various bone types and soft tissues in rat
por: Savisto, Nina, et al.
Publicado: (2023)

Head and neck squamous cell carcinoma cell lines have an immunomodulatory effect on macrophages independent of hypoxia and toll-like receptor 9
por: Ishizu, Tamiko, et al.
Publicado: (2021)

CD73 facilitates EMT progression and promotes lung metastases in triple-negative breast cancer
por: Petruk, Nataliia, et al.
Publicado: (2021)

Direct Comparison of [(18)F]F-DPA with [(18)F]DPA-714 and [(11)C]PBR28 for Neuroinflammation Imaging in the same Alzheimer’s Disease Model Mice and Healthy Controls
por: López-Picón, Francisco R., et al.
Publicado: (2021)

Alendronate-induced disruption of actin cytoskeleton and inhibition of migration/invasion are associated with cofilin downregulation in PC-3 prostate cancer cells
por: Virtanen, Sanna S., et al.
Publicado: (2018)

Evaluation of PET Imaging Performance of the TSPO Radioligand [(18)F]DPA-714 in Mouse and Rat Models of Cancer and Inflammation
por: Zheng, Jinzi, et al.
Publicado: (2015)

Initial experience with [(18)F]DPA-714 TSPO-PET to image inflammation in primary angiitis of the central nervous system
por: Backhaus, Philipp, et al.
Publicado: (2020)

[(18)F]SPA-RQ/PET Study of NK1 receptors in the Whole Body of Guinea Pig and Rat
por: Grönroos, Tove J., et al.
Publicado: (2019)

[(11)C]-DPA-713 and [(18)F]-DPA-714 as New PET Tracers for TSPO: A Comparison with [(11)C]-(R)-PK11195 in a Rat Model of Herpes Encephalitis
por: Doorduin, Janine, et al.
Publicado: (2009)

Evaluation of repeated [(18)F]EF5 PET/CT scans and tumor growth rate in experimental head and neck carcinomas
por: Silvoniemi, Antti, et al.
Publicado: (2014)

Repeatability of tumour hypoxia imaging using [(18)F]EF5 PET/CT in head and neck cancer
por: Silvoniemi, Antti, et al.
Publicado: (2017)

Uptake of [(18)F] EF5 as a Tracer for Hypoxic and Aggressive Phenotype in Experimental Head and Neck Squamous Cell Carcinoma()
por: Silén, Jonna, et al.
Publicado: (2014)

Enzyme inhibition of dopamine metabolism alters 6-[(18)F]FDOPA uptake in orthotopic pancreatic adenocarcinoma
por: Tuomela, Johanna, et al.
Publicado: (2013)

Population-based input function for TSPO quantification and kinetic modeling with [(11)C]-DPA-713
por: Akerele, Mercy I., et al.
Publicado: (2021)

Radiosynthesis of the norepinephrine transporter tracer [(18)F]NS12137 via copper‐mediated (18) F‐labelling
por: Lahdenpohja, Salla, et al.
Publicado: (2019)

Fast growth associated with aberrant vasculature and hypoxia in fibroblast growth factor 8b (FGF8b) over-expressing PC-3 prostate tumour xenografts
por: Tuomela, Johanna, et al.
Publicado: (2010)

(18)F-Radiolabeled Translocator Protein (TSPO) PET Tracers: Recent Development of TSPO Radioligands and Their Application to PET Study
por: Luu, Truong Giang, et al.
Publicado: (2022)

CD73 regulates zoledronate-induced lymphocyte infiltration in triple-negative breast cancer tumors and lung metastases
por: Petruk, Nataliia, et al.
Publicado: (2023)

[(18)F]PBR146 and [(18)F]DPA-714 in vivo Imaging of Neuroinflammation in Chronic Hepatic Encephalopathy Rats
por: Kong, Xiang, et al.
Publicado: (2021)

Antibody-mediated autoimmune encephalitis evaluated by (18)F-DPA714 PET/MRI
por: Shen, Ruinan, et al.
Publicado: (2022)

Longitudinal PET Imaging of Muscular Inflammation Using( 18)F-DPA-714 and (18)F-Alfatide II and Differentiation with Tumors
por: Wu, Chenxi, et al.
Publicado: (2014)

The translocator protein ligand [(18)F]DPA-714 images glioma and activated microglia in vivo
por: Winkeler, Alexandra, et al.
Publicado: (2012)

(18)F-DPA-714 PET Imaging for Detecting Neuroinflammation in Rats with Chronic Hepatic Encephalopathy
por: Kong, Xiang, et al.
Publicado: (2016)

Optimised GMP-compliant production of [(18)F]DPA-714 on the Trasis AllinOne module
por: Cybulska, Klaudia A., et al.
Publicado: (2021)

In response to: Anatomy of (18)F-GE180, a failed radioligand for the TSPO protein
por: Albert, Nathalie L., et al.
Publicado: (2020)

Fully Automated Synthesis of Novel TSPO PET Imaging Ligand [(18)F]Fluoroethyltemazepam
por: Fiorenza, Dario, et al.
Publicado: (2021)

[(125) I]IodoDPA-713 Binding to 18 kDa Translocator Protein (TSPO) in a Mouse Model of Intracerebral Hemorrhage: Implications for Neuroimaging
por: Bonsack, Frederick, et al.
Publicado: (2018)

Could (18) F-DPA-714 PET imaging be interesting to use in the early post-stroke period?
por: Ribeiro, Maria-Joao, et al.
Publicado: (2014)

[(18)F]DPA-714 PET Imaging of AMD3100 Treatment in a Mouse Model of Stroke
por: Wang, Yu, et al.
Publicado: (2014)

Lack of neuroinflammation in the HIV-1 transgenic rat: an [(18)F]-DPA714 PET imaging study
por: Lee, Dianne E., et al.
Publicado: (2015)

[(18)F]DPA-714 PET Imaging Reveals Global Neuroinflammation in Zika Virus-Infected Mice
por: Kuszpit, Kyle, et al.
Publicado: (2017)

PET imaging of retinal inflammation in mice exposed to blue light using [(18)F]-DPA-714
por: Chen, Yuan, et al.
Publicado: (2022)

PET imaging of retinal inflammation in mice exposed to blue light using [(18)F]-DPA-714
por: Chen, Yuan, et al.
Publicado: (2023)

Evidence of neuroinflammation in fibromyalgia syndrome: a [(18)F]DPA-714 positron emission tomography study
por: Mueller, Christina, et al.
Publicado: (2023)

Hypoxia regulates Toll-like receptor-9 expression and invasive function in human brain cancer cells in vitro
por: SANDHOLM, JOUKO, et al.
Publicado: (2014)

Chloroquine has tumor-inhibitory and tumor-promoting effects in triple-negative breast cancer
por: TUOMELA, JOHANNA, et al.
Publicado: (2013)

Comparative [18F]FDG and [18F]DPA714 PET imaging and time-dependent changes of brown adipose tissue in tumor-bearing mice
por: Niu, Na, et al.
Publicado: (2020)

[(18)F]CFT synthesis and binding to monoamine transporters in rats
por: Forsback, Sarita, et al.
Publicado: (2012)

Cannot write session to /tmp/vufind_sessions/sess_qfuenbv278b1hm61du6in2ain5