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Scalable recombinase-based gene expression cascades

Temporal modulation of the expression of multiple genes underlies complex complex biological phenomena. However, there are few scalable and generalizable gene circuit architectures for the programming of sequential genetic perturbations. Here, we describe a modular recombinase-based gene circuit arc...

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Detalles Bibliográficos
Autores principales:	Kim, Tackhoon, Weinberg, Benjamin, Wong, Wilson, Lu, Timothy K.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113245/ https://www.ncbi.nlm.nih.gov/pubmed/33976199 http://dx.doi.org/10.1038/s41467-021-22978-4

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