A Stat1 bound enhancer promotes Nampt expression and function within tumor associated macrophages

Tumor associated macrophage responses are regulated by distinct metabolic states that affect their function. However, the ability of specific signals in the local tumor microenvironment to program macrophage metabolism remains under investigation. Here, we identify NAMPT, the rate limiting enzyme in...

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Detalles Bibliográficos
Autores principales: Huffaker, Thomas B., Ekiz, H. Atakan, Barba, Cindy, Lee, Soh-Hyun, Runtsch, Marah C., Nelson, Morgan C., Bauer, Kaylyn M., Tang, William W., Mosbruger, Timothy L., Cox, James E., Round, June L., Voth, Warren P., O’Connell, Ryan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2021
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113251/
https://www.ncbi.nlm.nih.gov/pubmed/33976173
http://dx.doi.org/10.1038/s41467-021-22923-5

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