Meningeal inflammation in multiple sclerosis induces phenotypic changes in cortical microglia that differentially associate with neurodegeneration

Meningeal inflammation strongly associates with demyelination and neuronal loss in the underlying cortex of progressive MS patients, thereby contributing significantly to clinical disability. However, the pathological mechanisms of meningeal inflammation-induced cortical pathology are still largely...

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Detalles Bibliográficos
Autores principales: van Olst, Lynn, Rodriguez-Mogeda, Carla, Picon, Carmen, Kiljan, Svenja, James, Rachel E., Kamermans, Alwin, van der Pol, Susanne M. A., Knoop, Lydian, Michailidou, Iliana, Drost, Evelien, Franssen, Marc, Schenk, Geert J., Geurts, Jeroen J. G., Amor, Sandra, Mazarakis, Nicholas D., van Horssen, Jack, de Vries, Helga E., Reynolds, Richard, Witte, Maarten E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Berlin Heidelberg 2021
Materias:
Original Paper
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113309/
https://www.ncbi.nlm.nih.gov/pubmed/33779783
http://dx.doi.org/10.1007/s00401-021-02293-4

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