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Multi-step screening of neoantigens’ HLA- and TCR-interfaces improves prediction of survival

Improvement of risk stratification through prognostic biomarkers may enhance the personalization of cancer patient monitoring and treatment. We used Ancer, an immunoinformatic CD8, CD4, and regulatory T cell neoepitope screening system, to perform an advanced neoantigen analysis of genomic data deri...

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Detalles Bibliográficos
Autores principales:	Richard, Guilhem, De Groot, Anne S., Steinberg, Gary D., Garcia, Tzintzuni I., Kacew, Alec, Ardito, Matthew, Martin, William D., Berdugo, Gad, Princiotta, Michael F., Balar, Arjun V., Sweis, Randy F.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Nature Publishing Group UK 2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC8113358/ https://www.ncbi.nlm.nih.gov/pubmed/33976291 http://dx.doi.org/10.1038/s41598-021-89016-7

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